Xian-Yong Ma PhD
Associate Research Scientist in Pathology
Departments & Organizations
How do the key target proteins determine the status of cell differentiation and proliferation? How do the modifications of gene structure (DNA and core histone) cause global changes of gene expression pattern? My research employed multitude of molecular, cellular, physiological and bioinformatics techniques to investigate the molecular mechnisms and physiological function of interferon induced P202a, acute megakaryoblastic leukemia associated transcription factorRBM15, and Polycomb Repressive Group proteins SUZ12. The ongoing research topics including global interferes for binding pattern caused by fusion of polycomb protein JJAZ1 to transcription repressor JAZF1 and genome-wide exploration of cis regulatory regions bond with transcription factor JAZF1 using CHIP-sequencing analysis. more...
- Ph.D., Xiangya School of Medicine, Central South Univ, 1996
- Ma, X.Y., Ma, X. C., Wang, J.H. (2014) “Endometrial Carcinogenesis and Molecular Signaling Pathways.” American Journal of Molecular Biology. 4, 134-149.
- Ma, X.Y., Wang L., Jie Tang, et al (2012). “SPOC Domain of Mint Protein Induces Hematopoietic Differentiation Via BMP4/Smad5 pathway.” American Journal of Molecular Biology. 2(4) 304-317
- Ma, X.Y., Renda M.J. Wang L. et al. (2007).Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myelopid Differentiation. Mol. Cell. Biol. 27,3056-3064