Ronald A. Albright PhD

Associate Research Scientist in Pathology

Research Interests

x-ray crystallography; protein structure/function

Selected Publications

  • J Biol Chem. 2014 Feb 7;289:3294-3306. Albright RA, Ornstein DL, Cao W, Chang WC, Robert D, Tehan M, Hoyer D, Liu L, Stabach P, Yang G, De la Cruz EM, Braddock DT. Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke.
  • Blood. 2012 Nov 22;120(22):4432-4440. Albright RA, Chang WC, Robert D, Ornstein DL, Cao W, Liu L, Redick ME, Young JI, De La Cruz EM, Braddock DT. NPP4 is a procoagulant enzyme on the vascular endothelium.
  • J. Biol. Chem. 2011 Aug 26;286(34):30130-41. Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM. Kinetic analysis of Autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
  • J Biol Chem. 2007 Nov 30;282(48):35046-55. Epub 2007 Oct 10. Albright RA, Joh K, Morais-Cabral JH. Probing the structure of the dimeric KtrB membrane protein.
  • Cell. 2006 Sep 22;126(6):1147-59. Albright RA, Ibar JL, Kim CU, Gruner SM, Morais-Cabral JH. The RCK domain of the KtrAB K+ transporter: multiple conformations of an octameric ring.
  • Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3431-6. Albright RA, Matthews BW. How Cro and lambda-repressor distinguish between operators: the structural basis underlying a genetic switch.
  • J Mol Biol. 1998 Jul 3;280(1):137-51. Albright RA, Matthews BW. Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution.
  • Protein Sci. 1998 Jul;7(7):1485-94. Albright RA, Mossing MC, Matthews BW. Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein.
  • Biochemistry. 1996 Jan 23;35(3):735-42. Albright RA, Mossing MC, Matthews BW. High-resolution structure of an engineered Cro monomer shows changes in conformation relative to the native dimer.
  • Biochemistry. 1996 Jan 23;35(3):743-8. Mollah AK, Aleman MA, Albright RA, Mossing MC. Core packing defects in an engineered Cro monomer corrected by combinatorial mutagenesis.

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