Pei Hui PhD, MD
Associate Professor of Pathology and of Obstetrics, Gynecology, and Reproductive Sciences; Director, Clinical Molecular Diagnostics; Director, Gynecologic Pathology
Research Interests
GYN Pathology; Molecular Diagnostics
Research Summary
Dr. Hui's academic interests primarily focus on clinical and biological aspects of human neoplasia. Using molecular and genetic approaches, he has active research collaborations with clinical oncologists and basic science investigators in exploring the pathogenesis of several fascinating gynecological tumors including Type II endometrial carcinomas and gestational trophoblastic diseases. As medical director of the Molecular Diagnostics Laboratory, he has been exploring molecular methods in facilitating routine histological evaluations of neoplastic processes including lymphomas, translocation specific sarcomas and common solid tumors.
Extensive Research Description
Dr. Hui's academic interests primarily focus on clinical and biological aspects of human neoplasia. Using molecular and genetic approaches, he has active research collaborations with clinical oncologists and basic science investigators in exploring the pathogenesis of several fascinating gynecological tumors including Type II endometrial carcinomas and gestational trophoblastic diseases. As medical director of the Molecular Diagnostics Laboratory, he has been exploring molecular methods in facilitating routine histological evaluations of neoplastic processes including lymphomas, translocation specific sarcomas and common solid tumors.
Selected Publications
- Hui P. (Editor). Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology (Springer), 1st Edition, 2012, ISBN: 978-1-61779-393-6.
- Chhieng D and Hui P (Editors). Cytology and Surgical Pathology of Gynecologic Neoplasms (Springer), 1st Edition, 2010, ISBN 978-1-60761-163-9.
- Hui P. Molecular Diagnosis of Gestational Trophoblastic Disease (Invited review). Expert Review of Molecular Diagnostics. 2010, 10(8): 1023-1034.
- Buza N, Hui P. Gestational Trophoblastic Diseases: Histological Diagnosis in the Molecular Era (invited review). Diagnostic Histopathology. 2010, 16(11): 526-537.
- Lippata F, Parkash V, Talmor M, Bell S, Chen SP, Maric V, Hui P. Precise DNA Genotyping Diagnosis of hydatidiform moles. Journal of Gynecology and Obstetrics 2010, 115:784-794.
- Xu M, Schwartz PE, Rutherford TJ, Azodi M, Santin A, Silasi D, Martel M, Hui P. HER-2/neu Receptor Gene Status in Endometrial Carcinomas: A Tissue Microarray Study. Histopathology, 2010, 56:263-273.
- Siddon A, Hui P. Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal origin. International Journal of Gynecological Pathology. 2010, 29:394-397.
- Yan Z, Hui P. Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 cases. Applied Immunohistochemistry and Molecular Morphology, 2010, 18:75-79.
- Xu M, Yang Bin, Maria-Luisa Carcangiu, Hui P. Epithelioid Trophoblastic Tumor: Comparative Genomic Hybridization and Diagnostic DNA Genotyping. Modern Pathology, 2009, 22:232-238.
- Jorge D, Hui P. Lack of genetic association between exaggerated placental site reaction and placental site trophoblastic tumor. International Journal of Gynecological Pathology. 2008, 27:562-567.
Selected Publications
- Hui P. (Editor). Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology (Springer), 1st Edition, 2012, ISBN: 978-1-61779-393-6.
- Chhieng D and Hui P (Editors). Cytology and Surgical Pathology of Gynecologic Neoplasms (Springer), 1st Edition, 2010, ISBN 978-1-60761-163-9.
- Hui P. Molecular Diagnosis of Gestational Trophoblastic Disease (Invited review). Expert Review of Molecular Diagnostics. 2010, 10(8): 1023-1034.
- Buza N, Hui P. Gestational Trophoblastic Diseases: Histological Diagnosis in the Molecular Era (invited review). Diagnostic Histopathology. 2010, 16(11): 526-537.
- Lippata F, Parkash V, Talmor M, Bell S, Chen SP, Maric V, Hui P. Precise DNA Genotyping Diagnosis of hydatidiform moles. Journal of Gynecology and Obstetrics 2010, 115:784-794.
- Xu M, Schwartz PE, Rutherford TJ, Azodi M, Santin A, Silasi D, Martel M, Hui P. HER-2/neu Receptor Gene Status in Endometrial Carcinomas: A Tissue Microarray Study. Histopathology, 2010, 56:263-273.
- Siddon A, Hui P. Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal origin. International Journal of Gynecological Pathology. 2010, 29:394-397.
- Yan Z, Hui P. Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 cases. Applied Immunohistochemistry and Molecular Morphology, 2010, 18:75-79.
- Xu M, Yang Bin, Maria-Luisa Carcangiu, Hui P. Epithelioid Trophoblastic Tumor: Comparative Genomic Hybridization and Diagnostic DNA Genotyping. Modern Pathology, 2009, 22:232-238.
- Jorge D, Hui P. Lack of genetic association between exaggerated placental site reaction and placental site trophoblastic tumor. International Journal of Gynecological Pathology. 2008, 27:562-567.
- Bifulco C, Jonhson C, Hao LM, Kermalli H, Bell S, Hui P. Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis. American Journal of Surgical Pathology. 2008, 32(4):445-451.
- Hui P, Wang HL, Chu PG, Yang B, Huang J, Baergen RN, Sklar J, Yang XY, Soslow RA. Absence of Y Chromosome in Human Placental Site Trophoblastic Tumor. Modern Pathology 2007, 20(10):1055-60.
- Tallini G, Hui P. Molecular Diagnosis of Sarcomas, in Molecular Pathology in Clinical Practice, Chapter 28, edited by Leonard, Bagg, Caliendo, Kaul, Snow-Bailey and Van Deerlin (Springer), page 287-297, 2007.
- Fadare O, Parkash V, Carcangiu ML, Hui P. Epithelioid trophoblastic tumor: clinicopathological features with an emphasis on uterine cervical involvement. Modern Pathology. 2006, 19(1):75-82.
- Hui P, Fedoriw G. Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course. Nature Clinical Practice Oncololgy. 2005, 2(11):588-593.
- Hui P, Martel M, Parkash V.Gestational Trophoblastic Diseases: Recent Advances in Histopathologic Diagnosis and Related Genetic Aspects. Adv Anat Pathol. 2005, 12(3):116-125.
- Hui P, Kelly M, O'Malley DM, Tavassoli F, Schwartz PE. Minimal uterine serous carcinoma: a clinicopathological study of 40 cases. Modern Pathology. 2005, 18(1):75-82.
- Hui P, Riba A, Petrovic T, Johnson T, Baergen R, Ward D. Comparative genomic hybridization study of placental site trophoblastic tumor: successful analysis of four cases. Modern Pathology, 2004, 17:248-251.
- Hui P, Howe G, Crouch J, Qumsiyeh M, Tallini G, Flynn S, Smith B: Real-time RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: comparison with FISH and immunohistochemistry. Leukemia and Lymphoma, 2003, 44:1385-1394.
- Hui P, Parkash V, Perkins AS, Carcangiu ML. Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosome. Laboratory Investigation 2000, 80(6):965-72.
