Don Nguyen, PhD

Assistant Professor of Pathology

Research Interests

Inflammation; Lung Neoplasms; Neoplasm Metastasis; Pathology; Genomics; Neoplasm Micrometastasis

Public Health Interests

Cancer genetics; Genomics

Research Organizations

Pathology: Nguyen Lab

Signal Transduction

Stem Cell Center, Yale: Stem Cell Niche and Homing | Transcriptional Regulation of Stem and Progenitor Cells

Research Summary

Cancer metastasis remains an unresolved clinical and biological problem. This is particularly relevant in the case of thoracic malignancies, which can spread aggressively to multiple distant organs with limited opportunity for effective therapeutic intervention. Metastatic lung cancer cells are believed to acquire complex biological properties by deregulating pleiotoropic genetic programs and interacting with their microenvironment. My laboratory is interested in uncovering the molecular, cellular, and physiological determinants of metastasis by different lung cancers. In this endeavor, we utilize a variety of approaches such as animal modeling, cell biology, bioinformatics, and clinical validation.

Specialized Terms: Metastasis; Lung cancer; Cancer genomics; Tumor microenvironment

Selected Publications

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Contact Info

Don Nguyen, PhD
Office Location
Department Of PathologyBrady Memorial Laboratory
310 Cedar Street, Ste BML 348B

New Haven, CT 06510
Mailing Address
Department of Pathology310 Cedar Street
PO Box 208023

New Haven, CT 06520-8023

Nguyen lab website