Demetrios Braddock, MD, PhD
Associate Professor of Pathology
Departments & Organizations
Pathology: Anatomic Pathology; Anatomic Pathology: Hematopathology | Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology; Biochemistry, Biophysics and Structural Biology: crystallography, NMR, mass spectrometry, cryo-electron...faculty; Biochemistry, Biophysics and Structural Biology: Drug Design, Discovery and Mechanism; Biochemistry, Biophysics and Structural Biology: Transcriptional Regulation; Molecular Medicine, Pharmacology, and Physiology | Cancer Center, Yale: Hematology Program; Prostate and Urologic Cancers Program | Comprehensive Cancer Center: Gene Regulation and Functional Genomics | Structural Biology | Yale Medical Group: YMG Credentialed
Research Interests
Structural biology; Hematopathology; Genitourinary Pathologymore...
Education
- Ph.D., University of Chicago, 1994
- M.D., University of Chicago Pritzker School of Medicine, 1996
Selected Publications
- Saunders, L. P., Wenxiang Cao, W., Chang, W. C., Albright, W.A., Demetrios T. Braddock, D. T.,* De La Cruz, E.M.*, “Kinetic Analysis of Autotaxin Reveals Substrate-specific Catalytic Pathways and a Mechanism for Lysophosphatidic Acid Distribution” (2011) Journal of Biological Chemistry, Aug 26;286(34):30130-41.
- Braddock, D.T. “Autotaxin and lipid signaling pathways as anticancer targets” Current Opinion in Investigational Drugs (2010) 11:629-37.
- Hsiao, H.-H., Nath, A., Lin, C.-Y., Folta-Stogniew, E.J., Rhoades, E. and Braddock, D.T. “Quantitative Characterization of the Interactions between c-myc Transcriptional Regulators FUSE, FBP and FIR”, Biochemistry (2010), 49:4620-34.
