Graduate Courses (FAS)
PATH 600: Pathological Basis of Human Disease
Joseph Madri and staff
Fundamental principles underlying the pathological alterations in function and structure that constitute the reaction of the organism to injury. Pathology of diseases involving special organs and systems. Correlation of the clinical and anatomical manifestations is emphasized. For EPH graduate students and MSTP students who are required to take PATH 100 for graduate credit.
PATH 616: Autopsy Pathology
John Sinard and staff
Participation in the autopsy service with members of the house staff in pathology. Participation in autopsies and the presentation and review of the clinical and anatomical findings of postmortem examinations with senior members of the department. Opportunities exist for correlation studies with previous biopsies, and clinical investigative and cell biologic techniques in relation to necropsy material. Six weeks minimum, full time. Enrollment limited to two students.
PATH 617: Anatomic Pathology
José Costa and staff
The department offers an elective to medical students in the third and fourth years that provides a broad experience in general diagnostic techniques. Students have opportunities to participate in surgical pathology, cytology (including fine-needle aspiration), and autopsy. A daily diagnostic conference is scheduled for both residents and students, and an additional two hours of conference are provided each week exclusively for the students. In addition to direct responsibilities in the handling of the cases, the student has the opportunity to apply the special techniques of electron microscopy, immunohistochemistry, and flow cytometry. A minimum of four weeks is suggested for this elective. Five students are accommodated every four to six weeks.
PATH 618b: Clinical and Pathologic Correlates in Renal Disease
David Stern and Michael Kashgarian
A series of clinical pathologic conferences designed to illustrate clinicopathologic correlates in renal disease. At each session, one student acts as clinician and another as pathologist in the evaluation and discussion of case material from autopsies or renal biopsies. Discussions are informal, but require preparation in advance and all participants are expected to contribute in each session. One two-hour session per week for six weeks. Given once in spring term. Limited to twelve students. PATH 620a and b, Laboratory Rotations in Experimental Pathology. Laboratory rotations for first-year graduate students.
PATH 630b: Biomaterial-Tissue Interactions
An in-depth survey of the interactions between tissues and biomaterials, with an emphasis on the molecular- and cellular-level events that influence the performance and longevity of clinically relevant devices. Background in chemistry and cell biology is assumed. Open to advanced undergraduates with permission of the organizer.
PATH 650b: Cellular and Molecular Biology of Cancer
A comprehensive survey of cancer research from the cellular to the clinical level. The relationship of cancer to intracellular and intercellular regulation of cell proliferation is emphasized, as are animal models for cancer research. Background in molecular genetics and cell biology is assumed. Open to advanced undergraduates with permission of the Organizers.
Pathology 670b: Biological Mechanisms of Reaction to Injury
Michael Kashgarian, Jon Morrow, Vincent Marchesi, and A. Brian West
An introduction to human biology and disease as a manifestation of reaction to injury. Topics include organ structure and function, cell injury, circulatory and inflammatory responses, disordered physiology, and neoplasia.
PATH 680a: Seminar in Pharmacology and Molecular Medicine
Readings and discussion in topics relevant to cell biology, signal transduction, immunology, and molecular medicine. The overall theme of the papers discussed is pathogenesis of human infectious disease. The class emphasizes analysis of primary research literature and development of presentation skills.
PATH 690a: Molecular Mechanisms of Disease
This course covers aspects of the fundamental molecular and cellular mechanisms underlying various human diseases. Many of the disorders discussed represent major forms of infectious, degenerative, vascular, neoplastic, and inflammatory disease. Additionally, certain rarer diseases that illustrate good models for investigation and/or application of basic biologic principles are covered in the course. The objective is to highlight advances in experimental and molecular medicine as they relate to understanding the pathogenesis of disease and the formulation of therapies.
