Clara Abraham MD

Associate Professor of Medicine (Digestive Diseases)

Departments & Organizations

Yale Medical Group

Office of Student ResearchHTIInternal Medicine: Digestive Diseases: Inflammatory Bowel Disease Program

Research Interests

Regulation of the intestinal immune system; T cell trafficking and activation; Genetics and immunobiology of inflammatory bowel disease; host:microbe interactions. more...


  • BS, University of Illinois at Urbana-Champaign, 1985
  • M.D., University of Chicago Pritzker School of Medicine, 1989

Selected Publications

  • Lahiri A and Abraham C. Activation of Pattern Recognition Receptors Upregulates Metallothioneins, Thereby Increasing Intracellular Accumulation of Zinc, Autophagy, and Bacterial Clearance by Macrophages. Gastroenterology, epub 6/21/14.
  • Hedl M, Lahiri A, Ning K, Cho JH, Abraham C. Pattern Recognition Receptor Signaling in Human Dendritic Cells is Enhanced by ICOS Ligand and Modulated by the Crohn’s Disease ICOSLG Risk Allele. Immunity, 40:734-746, 2014.
  • Wu X, Lahiri A, Haines, GK III, Flavell RA, Abraham C. NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury. J Immunol. 192:3409-3418, 2014.



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