Laboratory Research

Yale Orthopaedic Biology Laboratories have extensive expertise in the molecular and cellular aspects of bone biology.

Among special services offered are the following:

• Molecular and cellular bone biology
• Histologic analyses of musculoskeletal tissues
• Preclinical animal studies

Yale Faculty:

• Veraragavan P. Eswarakumar, PhD
• Jonathan Grauer, M.D.
• Caren Gundberg, Ph.D.
• Mark Horowitz, Ph.D.
• Agnes Vignery, D.D.S., Ph.D.

Among special services offered are the following:

• Spine instability
• Whiplash
• Musculoskeletal control in low back pain patients

Yale Faculty:

• Paul Ivanic, Ph.D.

Orthopaedic Histology and Histomorphometry Laboratory

This laboratory provides histological preparations of both soft and hard tissues including undemineralized bone. Processing of bone requires specialized plastic embedding techniques utilizing either methylmethacrylate or glycolmethacrylate methods which are done on site. A wide array of special stains for bone tissues are performed on a routine basis. The laboratory is a fully equipped histology facility utilizing state of the art tissue processors, specialized microtomes, cryostats and knives designed to section hard tissues. High resolution digital photography of microscope slides is available.

• Plastic embedding of undemineralized bone
• Special stains
• Histomorphometry
• Routine histology/cryotomy
• Digital photography