Progesterone Supplementation

Progesterone Supplementation After Egg Retrieval:

Progesterone is a hormone that is produced by the ovarian cells that surround the egg and is essential to prepare the lining of the uterus for embryo attachment. Given that in IVF, these progesterone producing cells are aspirated along with the egg, patients undergoing IVF require supplementation with progesterone. Since progesterone producing cells are aspirated along with the egg, patients undergoing IVF require supplementation with progesterone.

When is Progesterone Started in an IVF Cycle:

Progesterone supplementation is started after the egg retrieval. Written instructions are provided on the timing and dosing regimen of progesterone supplementation (Crinone, Endometrin, Progesterone in Oil).

Which Type of Progesterone is Preferable:

Progesterone is available as vaginal suppositories, tablets, cream and as intramuscular injectable preparations. All formulations are comparable and your insurance coverage may restrict the choice of progesterone prescribed.

How Long is Progesterone Continued:

You will continue Progesterone supplementation at least until the day of your blood pregnancy test. If you are pregnant, you will continue Progesterone supplementation until 9-10 weeks of pregnancy. All patients who are not pregnant (as determined by a negative pregnancy test) will be instructed to stop progesterone supplementation, and should expect a period within a few days of stopping this treatment.