Project I

Role of Toll-like receptors in trophoblast immune regulation

Publications

Gervasi MT, Romero R, Bracalente G, Chaiworapongsa T, Erez O, Dong Z, Hassan SS, Yeo L, Yoon BH, Mor G, Barzon L, Franchin E, Militello V, Palù G, Viral invasion of the amniotic cavity (VIAC) in the midtrimester of pregnancy. J Matern Fetal Neonatal Med. 2012 Apr 23. PMID: 22524157

Holmberg JC, Haddad S, Wünsche V, Yang Y, Aldo PB, Gnainsky Y, Granot I, Dekel N, Mor G, An in vitro model for the study of human implantation Am J Reprod Immunol. 2012 Feb;67(2):169-78 PMID: 22151560 

Ramhorst R, Fraccaroli L, Aldo P, Alvero AB, Cardenas I, Leirós CP, Mor G, Modulation and recruitment of inducible regulatory T cells by first trimester trophoblast cells Am J Reprod Immunol. 2012 Jan;67(1):17-27 PMID: 21819477 

Wang B, Koga K, Osuga Y, Cardenas I, Izumi G, Takamura M, Hirata T, Yoshino O, Hirota Y, Harada M, Mor G, Taketani Y, Toll-like receptor-3 ligation-induced indoleamine 2, 3-dioxygenase expression in human trophoblasts Endocrinology. 2011 Dec;152(12):4984-92 PMID: 21952237 

Mor G, Cardenas I, Abrahams V, Guller S, Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad Sci. 2011 Mar;1221:80-7 PMID: 21401634 

Atay S, Gercel-Taylor C, Suttles J, Mor G, Taylor DD, Trophoblast-derived exosomes mediate monocyte recruitment and differentiation Am J Reprod Immunol. 2011 Jan;65(1):65-77 PMID: 20560914 

Cardenas I, Mor G, Aldo P, Lang SM, Stabach P, Sharp A, Romero R, Mazaki-Tovi S, Gervasi M, Means RE, Placental Viral Infection Sensitizes to Endotoxin-Induced Pre-Term Labor: A Double Hit Hypothesis. Am J Reprod Immunol. 2010 PMID: 20712808 

Aldo PB, Mulla MJ, Romero, R, Mor G, Abrahams VM, Viral ssRNA induces first trimester trophoblast apoptosis through an inflammatory mechanism, American Journal of Reproductive Immunology 2010 1;64(1):27-37 PMID: 20175771 

Peng B, Koga K, Cardenas I, Aldo P, Mor G, Phagocytosis of Apoptotic Trophoblast Cells by Human Endometrial Endothelial Cells Induces Proinflammatory Cytokine Production. Am J Reprod Immunol. 2010 1;64(1):12-9. PMID: 20219062 

Straszewski-Chavez SL, Abrahams VM, Aldo PB, Romero R, Mor G, AKT controls human first trimester trophoblast cell sensitivity to FAS-mediated apoptosis by regulating XIAP expression, Biol Reprod. 2010 Jan;82(1):146-52. PMID: 19726736 

Koga K, Mor G, Toll-Like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders, Am J Reprod Immunol. 2010 63(6):587-600. PMID 20367625

Mor G, Cardenas I, The immune system in pregnancy: a unique complexity, Am J Reprod Immunol. 2010 63(6):425-33. PMID: 20367629 

Sharp AN, Heazell AE, Crocker IP, Mor G, Placental Apoptosis in Health and Disease, Am J Reprod Immunol. 2010 PMID: 20367628 

Gnainsky Y, Granot I, Aldo PB, Barash A, Or Y, Schechtman E, Mor G, Dekel N., Local injury of the endometrium induces an inflammatory response that promotes successful implantation, Fertil. Steril, 2010 PMID: 20338560  

Straszewski-Chavez SL, Abrahams VM, Alvero AB, Aldo PB, Ma Y, Guller S, Romero R, Mor G, The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line, Swan 71 2009 Nov;30(11):939-48. PMID:19766308 

Cardenas I, Means RE, Aldo PB, Koga K, Lang SM, Booth C, Manzur A, Oyarzun E, Romero R, Mor G, Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor. J Immunol. 2009 185(2):1248-57. PMID: 20554966