Xiao-Bing Gao PhD

Associate Professor of Comparative Medicine and of Obstetrics, Gynecology, and Reproductive Sciences

Departments & Organizations

Office of Student ResearchComparative Medicine: Integrative Cell Signaling & Neurobiology of Metabolism (ICSNM)Obstetrics, Gynecology & Reproductive Sciences: Reproductive Neurosciences Group

Research Interests

Neurotransmission; Neurotransmitter response and synaptic plasticity; Cellular physiology of neuropeptides (hypocretin/orexin, melanin concentrating hormone, neuropeptide Y, ghrelin, leptin, and a-MSH); Ion channels (Na+, Ca2+, K+ channels); Electrophysiology/patch clamp recording; calcium imaging; Hypothalamus/lateral hypothalamic area; Energy homeostasis/feeding regulation; Sleep homeostasis and regulation; Drug addiction more...


  • Ph.D., Shanghai Institute of Physiology, China, 1996

Selected Publications

  • Liu, Z.W., Faraguna, U., Cirelli, C., Tononi, G., Gao, X.B. (2010) Direct evidence for wake-related increases and sleep-related decreases in synaptic strength in rodent cortex. J Neuroscience 30: 8671-8675.
  • Rao, Y., M. Lu, F. Ge, D.J. Marsh, S. Qian, A.H. Wang, M.R. Picciotto, X.-B. Gao. (2008) Regulation of synaptic efficacy in hypocretin/orexin containing neurons by melanin concentrating hormone in the lateral hypothalamus. Journal of Neuroscience 28: 9101-9110.
  • Rao, Y., Z.-W. Liu, E. Borok, R.L. Rabenstein, M. Shanabrough, M. Lu, M.R. Picciotto, T.L. Horvath, and X.-B. Gao. (2007) Prolonged wakefulness induces experience-dependent synaptic plasticity in hypocretin/orexin neurons. Journal of Clinical Investigation 117: 4022-4033.



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