Dr. Abrahams' lab studies Reproductive Immunology with a focus on the impact the immune system and immunological processes have on pregnancy outcome. Her research is concentrated on three main areas:1. Innate immune responses to infection at the maternal-fetal interface
2. Mechanisms of antiphospholipid antibody-induced pregnancy complications
3. The role of placental microparticles in the pathogenesis of preeclampsia
Dr. Mak has three main areas of research interest:
- Understanding the role of a translational regulator, Pumilio, in the acquisition of the primordial follicle pool, oocyte maturation and maternal-to-zygotic transition. These studies will elucidate the genes important in establishing the ovarian reserve in women and identify new biomarkers of oocyte and embryo quality.