Neuroendocrinology and Metabolism
The research focus of Dr. Diano's laboratory is to study intracellular and intercellular mechanisms in neuronal populations of the hypothalamus that regulate energy and glucose metabolism.
Dr. Huang’s research interest has been the post-transcriptional regulation of gene expression in the mammalian system. While studying the rules and mechanisms that govern the nucleocytoplasmic transport of mRNAs, she discovered that a subset of SR proteins (originally thought to be only splicing factors) function as a new class of mRNA export factors.
Dr. Flannery is interested in the effect of insulin resistance and diabetes on endometrial pathology. Insulin resistance is an underlying problem in obesity, the Polycystic Ovary Syndrome, and Type 2 diabetes mellitus. Women with obesity, PCOS, or Type 2 diabetes mellitus have a higher risk of irregular bleeding, implantation failure, miscarriage, endometrial hyperplasia, and endometrial carcinoma.
Our neuromorphology laboratory is involved in a broad array of studies concerning the actions of gonadal hormones and the xenoestrogen, bisphenol A on the central nervous system of both rodents and subhuman primates.
The Seli lab's main research interests are:1. Regulation of gene expression during oocyte and pre-implantation embryo development
2. Assessment of embryo viability in assisted reproductive technologies
3. The role of translational regulation of cytokine and growth factor expression in the pathogenesis of endometriosis
My research program addresses reproductive hormone effects on temperature and body fluid regulation, cardiovascular and autonomic function, and exercise responses. The lab's interests include environmental physiology, reproductive hormone effects on temperature and body fluid regulation, Polycystic Ovary Syndrome, orthostatic tolerance and blood pressure regulation