Dr. Flannery is interested in the effect of insulin resistance and diabetes on endometrial pathology. Insulin resistance is an underlying problem in obesity, the Polycystic Ovary Syndrome, and Type 2 diabetes mellitus. Women with obesity, PCOS, or Type 2 diabetes mellitus have a higher risk of irregular bleeding, implantation failure, miscarriage, endometrial hyperplasia, and endometrial carcinoma.
Dr. Huang’s research interest has been the post-transcriptional regulation of gene expression in the mammalian system. While studying the rules and mechanisms that govern the nucleocytoplasmic transport of mRNAs, she discovered that a subset of SR proteins (originally thought to be only splicing factors) function as a new class of mRNA export factors.
Gabor Huszar M.D., a Senior Research Scientist, is an accomplished investigator in several areas of Reproductive Science.
Dr. Mak has three main areas of research interest:
- Understanding the role of a translational regulator, Pumilio, in the acquisition of the primordial follicle pool, oocyte maturation and maternal-to-zygotic transition. These studies will elucidate the genes important in establishing the ovarian reserve in women and identify new biomarkers of oocyte and embryo quality.
Dr. Seli's lab research interests are:
- Translational regulation of gene expression during oocyte and pre-implantation embryo development
- Assessment of embryo viability in assisted reproductive technologies
- Reproductive aging
- The role of translational regulation of cytokine and growth factor expression in the pathogenesis of endometriosis
Dr. Taylor's lab studies Reproductive Endocrinology with a focus on endometrial pathophysiology. Ongoing research focuses on the role of genetics, epigenetics, environmental disruptors in endometrial health and disease as well as stem cells in endometrial repair and tissue engineering