Research in the Department of Neurosurgery, Yale University School of Medicine, covers a broad range of interests, reflecting the diversity of contemporary state-of-the-art neuroscience research. Our programs include translational efforts based on work with patient populations to the most fundamental cellular and molecular issues of central nervous system organization and function. The specific interests of our faculty are described in detail on their individual WEB pages which also include links to examples of their most recent publications. Our research programs are well supported with multiple NIH grants, 1 of which is a large multi-investigator program project. Support is provided by several NIH institutes including NINDS, NIDCD, NIA, and NCI. In addition, the support of special interest foundations and endowments continues to be an important component of our research efforts. Our research facilities are predominately located on the 4th floors of Farnum Memorial Building and Tompkins, but our faculty also maintain labs in TAC and the West Haven Veterans Hospital. In addition, our research programs are broadly collaborative throughout the university and medical school including close ties with the Departments of Biomedical Imaging, Biomedical Engineering, Genetics, Neurology, Molecular Biology and Biochemistry, and Neurobiology, among others. In addition to the primary faculty, the research effort of the department hosts 5 Associate Research Scientists, 8 Postdoctoral Fellows/Associates, 1 M.D./Ph.D. candidate, several Ph.D. candidates and multiple M.D. candidates as well as undergraduates. Collectively, it is a very rich environment providing for stimulating discussions and collaborations.