Joseph Massa Piepmeier MD
Nixdorff-German Professor of Neurosurgery; Vice Chair of Clinical Affairs, Neurosurgery; Section Chief, Neuro-Oncology; Director, Surgical Neuro-Oncology; Clinical Research Program Leader, Brain Tumor Program, Yale Cancer Center
Research Interests
neuro-oncology; acoustic neuroma; general neurosurgery; brain and spinal cord cancer; brachytherapy; stereotactic needle biopsy
Research Summary
Yale's neuro-oncology program puts together all of the components
critical to managing patients with brain tumors: comprehensive evaluation
and diagnosis, leading edge treatment options, thorough follow-up and
psychosocial support. Patients are welcome whether they are newly diagnosed
or have already received extensive treatment.
Calls from referring physicians, patients or their families are handled
by an experienced clinical care coordinator. The coordinator ensures that
appropriate appointments are made quickly. New patients with brain tumors
are usually seen in the oncology clinic of the Yale Cancer Center within
a couple of days. The care coordinator also acts as the patient's interface
with the various medical specialists who are called into play in each
treatment plan.
The patient is the focus of all of the diagnosis and treatment skills
Yale's interdisciplinary team of specialists brings to the service. Neuro-oncology
surgeons, radiation oncologists, neuroradiologists, medical oncologists,
neurologists, neuropathologists and others meet weekly at a Tumor Board
Conference to arrive at the most appropriate treatment plan for each individual.
Because the Yale Cancer Center is an academic referral center, the teams
of specialists have an opportunity to treat the rarest as well as the
most common cancers. Because of the center's research and teaching mission,
its practitioners are well acquainted with the most advanced treatment
methods. Patients benefit from that knowledge and from specialized resources
such as a dedicated neurological intensive care unit and the latest imaging
technologies.
Selected Publications
- Sawyer A, Piepmeier J, Saltzman M: New Methods for Direct Delivery of Chemotherapy for Treating Brain Tumors. Yale Journal of Biology and Medicine,
- Kunwar S, Prados M, Chang S, Berger M, Lang F, Piepmeier J, Sampson J, Ram Z, Gutin P, Gibbons R, Aldape K, Croteau D, Sherman J, Puri R: Direct Intracerebral Delivery of Cintredekin Besudotox (IL13-PE38QQR) in Patients with Recurrent Malignant Glioma. J Clin Oncol 25(7):837-44, 2007
- Baehring J, Bi L, Bannyhk S, Piepmeier J, Fulbright R: Diffusion MRI in the early diagnosis of malignant glioma. J. Neuro-oncology,
- Piepmeier J, Thaiyananthan, T, Ocal, E: Principles of Neurosurgical Therapy. Practice and Principles of Neuro-oncology, Baehring J Piepmeier J (eds), 2006
- Lally B, Knisely J, Piepmeier J: The interactions of polarographic measurements of oxygen tension and histological grade in human glioma. in press The Cancer Journal.


