Z. Jimmy Zhou, PhD

Marvin L. Sears Professor of Ophthalmology and Visual Science and Professor of Cellular and Molecular Physiology and of Neurobiology; Vice Chairman and Director of Research, Ophthalmology and Visual Science

Contact Info

Z. Jimmy Zhou, PhD
Office Location
Department of Ophthalmology and Visual Science300 George Street, Ste Suite 8100D
New Haven, CT 06511
Mailing Address
Department of Ophthalmology & Visual ScienceYale University School of Medicine
300 George Street, Suite 8100

New Haven, CT 06510
Research Image 2

On the cover: Motion and motion direction, illustrated here by the movement of six pool balls in a "starburst shot," are first detected in the retina by a synaptic circuit involving starburst amacrine cells (shown with Lucifer yellow filling). In this issue, Lee et al. show that starburst cells corelease ACh and GABA onto direction-selective ganglion cells at spatially symmetric cholinergic and spatially asymmetric GABAergic synapses, respectively. The cholinergic transmission facilitates motion detection, while the GABAergic transmission mediates direction selectivity.