Janghoo Lim, PhD

Assistant Professor of Genetics

Research Interests

Research Organizations

Interdepartmental Neuroscience Program

Program in Cellular Neuroscience, Neurodegeneration and Repair

Research Summary

Neurological disorders affect millions of people worldwide, and health care costs related to treating these illnesses are enormous. They include a broad spectrum of brain problems such as birth defects, mental retardation, neuropsychiatric disorders, and neurodegenerative diseases.

The overall goal of my laboratory is to better understand the fundamental mechanisms of neural development and function, as well as its relevance to the pathogenesis of diverse human neurological disorders. The lab is focused on two major questions. First, how is neurogenesis regulated during embryonic and adult stages and how does its malfunction contribute to neurological problems? Second, what is the molecular and cellular basis of neurodegenerative diseases?

To achieve this goal, we utilize the combined approaches of biochemistry, cell biology, behavior, and molecular genetics with in vivo animal (e.g. Drosophila and mouse) models.

Extensive Research Description

Pathogenesis studies of polyglutamine diseases

Selected Publications

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Contact Info

Janghoo Lim, PhD
Lab Location
Boyer Center for Molecular Medicine
295 Congress Avenue, Ste BCMM 445

New Haven, CT 06510
Mailing Address
Boyer Center for Molecular Medicine295 Congress Ave. BCMM 454C
New Haven , CT 06510