David Zenisek PhD

Associate Professor of Cellular and Molecular Physiology and of Ophthalmology and Visual Science

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and PhysiologyInterdepartmental Neuroscience ProgramKavli Institute for Neuroscience | Cellular & Molecular Physiology: Membrane Protein Sorting and Trafficking; Neurobiology and Physiology of Synapses; Cell to Cell Communication; Physiology and Integrative Medical Biology Track; Graduate Program in Cellular and Molecular PhysiologyOphthalmology and Visual Science

Research Interests

Physiology and cell biology of the presynaptic terminal; Retinal Bipolar Neuron; Synaptic Terminal; Synaptic Ribbons; Vesicle Transport; Exocytosis; Endocytosis more...


  • Ph.D., State University of New York, 1998

Selected Publications

  • Mehta, B., Snellman, J., Chen, S., Li, W. and Zenisek, D. (2013) Synaptic ribbons influence the size and frequency of miniature-like evoked postsynaptic currents. Neuron, 77:516-527 PMCID: PMC3569740
  • Snellman, J., Mehta, B., Babai, N., Bartoletti, T.M., Francis, A., Akmentin, W., Matthews, G., Thoreson, W. and Zenisek, D. (2011) Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming. Nature Neuroscience.14: 1135-1141.
  • Francis, A., Mehta, B. and Zenisek, D. Development of new peptide-based tools for studying synaptic ribbon function. Journal of Neurophysiology, 2011, 166(2): 1028-1037.



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