Center for Neuroscience and Regeneration Research
The Yale Center for Neuroscience and Regeneration Research brings together multidisciplinary teams of researchers—molecular and cell biologists, physiologists, pharmacologists, stem cell biologists, computational biologists, and clinicians—in a focused effort to capitalize on the “molecular revolution” and discover new therapies that will restore and preserve function in nervous system injury and disease. Established in 1988, the Center is a model of inter-institutional cooperation that brings together the strengths of the Paralyzed Veterans of America, United Spinal Association, Department of Veterans Affairs, and Yale University School of Medicine in a collaborative effort, toward the development of effective treatments, and ultimately a cure, for spinal cord injury, multiple sclerosis and related disorders such as neuropathic pain syndromes, ischemic stroke and TBI. Two broad sets of approaches, cellular and molecular, address our goal of restoration and preservation of nervous system function. Major themes of our research are as follows:
- Transplantation-based approaches toward restoration of neurological function in the brain and spinal cord.
- Preservation of neurological function via mechanisms that can protect intact white and gray matter surrounding the injury site.
- Molecular biology and pathophysiological of sodium channels in human pain disorders.
- Molecular mechanisms of remissions in multiple sclerosis as a means to identifying strategies for restoration of neurological function.
For more information regarding the program, please visit their website.