We are a computational genetics group based in the Department of Neurology, Yale School of Medicine. We use genetics to discover and understand the mechanisms that give rise to disease. We are particularly interested in disorders of the immune system and brain.
We look for genetic factors that predispose to disease and try to understand the biology they perturb. We ask what genes are perturbed, what processes they participate in and whether these perturbations are sufficient to induce differences at the molecular and cellular levels. This gives us novel targets for biomarkers, diagnosis and treatment.
As you might have guessed, our expertise combines molecular biology, genetics, statistics and computer science. We have a diversity of backgrounds precisely because we work with data from disparate disciplines. If you are interested in collaboration or joining our group we would love to hear from you. For further information please visit our website.