Ralph Joseph DiLeone PhD

Professor of Psychiatry and Associate Professor of Neurobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and DevelopmentInterdepartmental Neuroscience ProgramNeurobiology: Kavli Institute for NeurosciencePsychiatry: Connecticut Mental Health Center; Molecular Psychiatry, Division of; Stress & Addiction Clinical Research Program; DiLeone Lab

Research Interests

Addictions; Animal Behavior; Ethology; Animal Nutrition; Diseases and Disorders; Drug Abuse; Eating Disorders; Etiology; Evolution; Genetic Manipulation; Natural History; Obesity; Psychiatry more...


  • B.A., Skidmore College, 1992
  • Ph.D., Stanford University, 1998

Selected Publications

  • Land BB, Narayanan NS, Liu R-J, Gianessi CA, Brayton CE, Grimaldi DM, Sarhan M, Guarnieri DJ, Deisseroth K, Aghajanian GK, and RJ DiLeone (2014). Medial prefrontal D1 dopamine neurons control food intake. Nature Neuroscience, 17(2):248-53.
  • Land BB, Brayton CE, Furman KE, LaPalombara Z, and RJ DiLeone (2014). Optogenetic inhibition of neurons by internal light production. Frontiers in Behavioral Neuroscience: 8:108.
  • Naryanan, N.S., Land, B.B., Solder, J.E., Deisseroth, K., and R.J. DiLeone (2012) Prefrontal D1 dopamine signaling is required for temporal control. Proceedings of the National Academy of Sciences, 109(50) 20726-31.



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