Nihal C. DeLanerolle DPhil, D.Sc.

Professor of Neurosurgery and of Neurobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience

Interdepartmental Neuroscience Program



Research Interests

Molecular and cellular neuropathology of human seizure foci; Development of animal models of human temporal lobe epilepsy; Neuropathology of Traumatic brain injury more...


  • D.Phil., University of Sussex, England, 1972

Selected Publications

  • Eid, T., Ghosh, A., Wang, Y., Beckstrom, H., Zaveri, H., Lee, T-S., Lai, J.K.C., Malthankar_Phatak, G.H., and de Lanerolle, N.C. (2008) Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats. Brain (July 6) doi:10.1093/brain/awn133
  • Lee, T-S., Mane, S., Eid, T., Zhao, H., Lin, A., Guan, Z., Kim, J.H., Schweitzer, J., King-Stevens, D., Weber, P., Spencer, S.S., Spencer, D.D., and de Lanerolle, N.C. (2007) Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol. Med. 13: 1-13
  • Eid, T., Hammer, J., Runden-Pran, E., Roberg, B., Thomas, M.J., Osen, K., Davanger, S., Laake, P., Torgner, I.A., Lee, T-S.W., Kim, J.H., Spencer, D.D., Ottersen, O.P., and de Lanerolle, N.C. (2007) Increased expression of phosphate activated glutaminase in hippocampal neurons in human mesial temporal lobe epilepsy. Acta Neuropathol. 113: 137-152



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