John H. Krystal MD

Robert L. McNeil, Jr. Professor of Translational Research and Professor of Neurobiology; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Biographical Info

Dr. Krystal is a leading expert in the areas of alcoholism, schizophrenia, and post-traumatic stress disorder. His work links psychopharmacology, neuroimaging, and molecular genetics to study the neurobiology and to develop novel treatments for these disorders.

He is a member of the Institute of Medicine of the National Academies. He also serves in a variety of advisory and review capacities for NIAAA, NIMH, Wellcome Trust, Brain and Behavior Research Foundation, and the Karolinska Institutet.

He previously served on the National Alcohol Abuse and Alcoholism Advisory Council (NIAAA), the Department of Defense Psychological Health Advisory Committee, the NIMH Board of Scientific Counselors (chair, 2005-2007), American College of Neuropsychopharmacology (president, 2012), and International College of Neuropsychopharmacology (president-elect).

Dr. Krystal also edits the journal, Biological Psychiatry (impact factor: 9.472).

International Activity

  • Schizophrenia Treatment
    Taichung, Taiwan(2013 - 2014)
    Consulting regarding novel treatments for schizophrenia and ketamine-related psychosis.
  • Neuroimaging studies of schizophrenia and related disorders
    Chengdu, China(2012 - 2014)
    Neuroimaging studies of brain structure and function associated with psychosis
  • Rapid Acting Antidepressant Treatment
    Taipei, Taiwan(2012 - 2014)
    Consulting to a study conducted evaluating the antidepressant effects of ketamine, led by Dr. Tung-Ping (Tom) Su.
  • Ketamine Psychosis
    Guangzhou, China(2010 - 2014)
    Studying the phenomenology and genetics of ketamine psychosis in relation to schizophrenia
  • Clinical Archives Project Cherite Hospital
    Berlin, Germany(2006 - 2014)
    The Department of Psychiatry at Cherite Hospital in Berlin has long been a home to ethical and compassionate treatment of patients. However, in the period leading up to World War II, its psychiatry leadership involved the hospital in the emerging eugenics movement. This work, contributed to the emergence of the Nazi T4 Program, which introduced forced sterilization and then "euthanasia" for individuals with chronic mental illness. I serve on the External Advisory Board to a historical program, commissioned by Dr. Andreas Heinz, chair of Psychiatry at Cherite, to review the hospital clinical records and to document the participation of this hospital in these atrocities.

Education & Training

University of Chicago (1980)
Yale University (1984)
Yale University School of Medicine, Psychiatry (1984 - 1988)

Honors & Recognition

  • Kempf Award for Contributions to Schizophrenia Research through Research and Mentorship
    American Psychiatric Association (06/2005)
  • Anna-Monika Prize in Depression Research
    Anna-Monika Foundation, Munich, Germany (10/2009)
  • Stanley Dean Award for Schizophrenia Research
    American College of Psychiatry (02/2010)
  • Joel Elkes Award
    American College of Neuropsychopharmacology (2001)
  • Jack Mendelson Award for Clinical Research
    National Institute on Alcohol Abuse and Alcoholism (2010)
  • Member
    Institute of Medicine, U.S. National Academies of Science (2010)
  • Exemplary Psychiatrist Award
    National Alliance on Mental Illness (2011)
  • Paul Hoch Research Award
    American Psychopathological Association (2014)

Professional Service

  • President, American College of Neuropsychopharmacology (12/13/2011 - 12/13/2012)
  • President-Elect, International College of Neuropsychopharmacology (07/01/2014 - 07/01/2016)

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