Fred Gorelick MD

Professor of Medicine (Digestive Diseases) and of Cell Biology; Associate Director, Yale M.D., Ph.D. Program

Departments & Organizations

Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Cell Biology: Cancer cell biology

Internal Medicine: Digestive Diseases: Liver Center


Research Interests

Exocrine pancreas; pancreatitis; intracellular proteolysis; vacuolar ATPase; AMPK; protein kinase C more...


Education

  • M.D., University of Missouri, 1973

Selected Publications

  • Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F. Vacuolar-ATPase modulates MMP activities and invasive properties in human pancreatic ductal adenocarcinoma (PDAC). In Press, Laboratory Investigation NIHMS257466
  • Lugea A, Tischler D, Nguyen J, Gong J, Gukovsky I, French SW, Gorelick FS, Pandol SJ. Adaptive Unfolded Protein Response Attenuates Alcohol-induced Pancreatic Damage. Gastroenterology 2011 140(3):987-997. PMC3057335
  • Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH. Low extracellular pH modulates calcium signaling in the pancreatic acinar cell. J. Biological Chemistry 2011 286(3):1919-26 PMC330423

more...

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