William H Konigsberg PhD

Professor of Molecular Biophysics and Biochemistry

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural BiologyCancer Genetics & GenomicsMolecular Biophysics and Biochemistry: DNA Replication and RepairDiscovery to Cure Internship

Research Interests

Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules more...


  • Ph.D., Columbia University, 1956

Selected Publications

  • Xia, S., Vashishtha, A.K., Bulkley, D., Eom, S.H., Wang,J., Konigsberg, W.H. (2012) Contribution of Partial Charge Interactions and Base-Stacking to the Efficiency of Primer-Extension at and beyond Abasic Sites in DNA. Biochemistry 51:4922-4931.
  • Xia, S. Beckman, J., Wang, J., Konigsberg, W.H. (2012) Using a Fluorescent Cytosine Analogue tC(o) to Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Biochemistry 51: 4609-4617.
  • Xia, S., Christian, T.D., Wang, J., Konigsberg, W.H. (2012) Probing Minor Groove Hydrogen Bonding Interactions between RB69 DNA Polymerase and DNA. Biochemistry 51:4343-53.



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