Mark J Solomon PhD

Professor of Molecular Biophysics and Biochemistry

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Signal Transduction

Molecular Biophysics and Biochemistry: Cell Cycle and Transcriptional Regulation | Solomon lab

Signal Transduction

Research Interests

Cell cycle; Ubiquitin-mediated proteolysis; Anaphase-promoting Complex  more...


  • B.A., Princeton University, 1981
  • Ph.D., Massachusetts Institute of Technology, 1986

Selected Publications

  • Burton, J.L. and M.J. Solomon. (2007). Mad3p, a Pseudosubstrate Inhibitor of APC-Cdc20 in the Spindle Assembly Checkpoint. Genes & Dev., 21: 655-667.
  • Ostapenko, D., J.L. Burton, R. Wang, and M.J. Solomon. (2008). Pseudosubstrate Inhibition of the Anaphase-Promoting Complex by Acm1: Regulation by Proteolysis and Cdc28 Phosphorylation. Mol. Cell. Biol., 28: 4653-4664.
  • Cheng, A. and M.J. Solomon. (2008). Speedy/Ringo C Regulates S and G2 Phase Progression in Human Cells. Cell Cycle, 7: 3037-3047.



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