Publications

Cleary ML, Epstein MA, Finerty S, Dorfman RF, Borkmann GW, Kirkwood JK, Morgan AJ, Sklar J. Individual tumours of multifocal EB virus-induced malignant lymphomas in tamarins arise from different B cell clones. Science 1985; 228:722-724.

Shearer WT, Ritz J, Finegold MJ, Guerra IC, Rosenblatt HM, Lewis DE, Pollack MS, Taber CH, Srimaya CV, Cleary ML, Grumet FC, Warnke R, Sklar J. Epstein-Barr virus-assoicated B cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency. New Engl J Med 1985; 312:1151-1159.

Cleary M, Meeker T, Levy S, Lee B, Trela M, Sklar J, Levy R. Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B cell lymphoma. Cell 1986; 44:97-106.

Weiss ML, Wood G, Trela M, Warnke R, Sklar J. Clonal T cell populations in lymphomatoid papulosis: evidence of a lymphoproliferative origin for a clinically benign disease. New Engl J Med 1986; 315:475-479.

Cleary ML, Smith SD, Sklar J. Cloning and structural analysis of cDNAs for the bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from t(14;18) chromosomal translocation. Cell 1986; 47:19-28.

Reynolds TC, Smith SD, Sklar J. Analysis of DNA surrounding the breakpoints of chromosomal translocation involving the beta T cell receptor gene in human lymphoblastic neoplasms. Cell 1987; 50:107-117.

Weiss LM, Movahed LA, Warnke RA, Sklar J. Detection of Epstein-Barr viral DNA in Reed-Sternberg cells of Hodgkin's disease. New Engl J Med 1989; 320:502-506.

Tycko B, Palmer JD, Sklar J. T-cell receptor gene trans-rearrangements: chimeric gamma-delta genes in normal lymphoid tissues. Science 1989; 245:1242-1246.

Bourguin A, Tung RM, Galili N, Sklar J. Rapid, non-radioactive detection of clonal T cell receptor gene rearrangements in lympoid neoplasms. Proc Natl Acad Sci USA 1990; 87: 8536-8540.

Ellisen LW, Bird J, West DC, Soreng AL, Reynolds TC, Smith SD, Sklar J. TAN-1, the human homologue of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991; 66:649-661.

Mashal RD, Koontz J, Sklar JL. Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases. Nature Genet 1995; 9:177-183.

Luo B, Aster JC, Hasserjian RP, Kuo F, Sklar J. Isolation and functional analysis of a cDNA for human JAGGED2, a gene encoding a ligand for the NOTCH1 receptor. Mol Cell Biol 1997; 17:6057-6067.

Kuo FC, Sklar J. Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers. J Exp Med 1997; 186:1547-1556.

Morgan J, Yi Y, Kuo F, Borowsky A, Kuo F, Nourmand N, Koontz JI, Reynolds C, Soreng L, Griffin C, Harris NL, Weisenburger D, Pinkus G, Fletcher J, Sklar J. Breakpoints of the t(11;18)(q21;q21) in MALT lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18. Cancer Res 1999; 59: 6205-6213.

Koontz JI, Soreng AL, Nucci M, Kuo FC, Pauwels P, van den Berghe H, Dal Cin P, Fletcher JA, Sklar J. Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. Proc Natl Acad of Sci USA 2001; 98: 6348-6353.

Li H, Ma X, Wang J, Koontz J, Nucci M, Sklar J. Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. Proc Natl Acad Sci USA 2007; 104: 20001-20006.

Li H, Wang J, Mor G, Sklar J. A neoplastic gene fusion mimics trans-splicing of RNAs in normal cells. Science, in press.