About Our Research

Stem cells have two unique features; self-renewal and differentiation potential. Particularly, embryonic stem cells (ESCs) derived from inner cell mass of blastocyst are pluripotent, and can give rise to cells of three germ layers. Recent studies have shown that ectopic expression of a set of defined transcription factors or genes can result in a cell fate change, generating induced pluripotent stem cells, neurons, cardiomyocytes, hematopoietic cells, or hepatocytes. Using these tools, currently, we investigate the neurodevelopmental disorders.