Joseph Madri, PhD, MD
Professor of Pathology
Laboratory PI

Yue Wu, MD, PhD
3rd Year Pathology Resident and former Associate Research Scientist
Yue, now a third year Pathology Resident, is working on elucidating the roles of PECAM-1 (CD31) in bone metabolism, specifically investigating its roles in modulating crosstalk between hematopoiesis and bone cells. She also is developing a selected battery of proteins as markers for early diagnosis of intraventricular and intracerebral hemorrhage in premature newborn.

Qi Li, PhD
Associate Research Scientist
Qi is working on elucidating the dynamic crosstalk between endothelial cells and neural stem cells in the subventricular neurovascular niche and their responsiveness to the chronic sublethal hypoxic insult experienced by many prematurely-born infants. She is using two mouse strains that mimic the range of responsiveness to chronic sublethal hypoxia experienced in the premature newborn population as a model system.

Kelly  Romano
Graduate Student, Molecular & Cellular Genetics & Development
Kelly is investigating the roles of CD44 in the process of lymphocyte endothelial cell transmigration in the central nervous system.

Chan Park, PhD
Visiting Scientist, Korea
Chan, an Assistant Professor of the Department of Anatomy and Neurobiology School of Medicine, Kyung Hee University Seoul 130-701, Korea, (E-mail: psychan@khu.ac.kr) is investigating the differential recovery of C57BL/6 and CD1 mice following a defined cortical sensorimotor injury model that he developed. Specifically, he is studying the neural stem cell and vascular responses in the subventricular zone.

Vladimir Glinskii
Yale Medical Student
Vlad is validating a selected number of SNPs as markers for early diagnosis of intraventricular and intracerebral hemorrhage in premature newborn.

Sandra Canosa, MS
Associate in Research II
Sandra is investigating the role of PECAM-1 as a modulator of osteoclastogenesis and osteoporosis. She is investigating specific tyrosine and serine phsophorylations and polymorphisms as modulators of these processes. She also is developing a selected battery of proteins and SNPs as markers for early diagnosis of intraventricular and intracerebral hemorrhage in premature newborn. She also participates in Kelly’s and Qi’s projects.

Michael Michaud, MS
Associate in Research I
Michael is involved in maintaining our mouse colony, specifically setting up specific matings and genotyping, phenotyping and characterizing the behaviors of the various knock out and transgenic mice. He also participates in Qi's, Kelly’s and Chan’s projects.

Anjali Nath, PhD
Former Graduate Student and Postdoctoral Fellow
Anjali demonstrated the effectiveness of a protein profiling approach in the identification of novel proteins involved in epithelial to mesenchymal transformation in the cardiac cushions during heart development and is elucidating the signaling pathways that a selected number of these proteins play roles in. She is currently a postdoctoral fellow at Harvard University.

Jennifer Long
Former Graduate Student, Cellular & Molecular Physiology
Jennifer Long (now Baughman). Jennifer investigated the molecular mechanisms of vascular sympathetic innervation. Specifically she identified attractive and repulsive signaling molecules differentially expressed by innervated and non-innervated vessels using traditional cell biological and pharmacological methods and suppressive hybridization techniques to identify novels signaling molecules involved in this process. The importance of understanding and controlling sympathetic innervation in specific vascular beds is thought to be important and may have important clinical implications in a variety of clinical settings including its disruption following heart transplantation. She is currently a postdoctoral fellow at Harvard University.

Jaime Liu, PhD
Visiting Scientist, China
Jaime, an Associate Professor at Jinlin University, China, investigated the effects of endothelial derived soluble factors (BDNF, VEGF and SDF-1) on the migratory and differentiation behaviors of neural stem cells in direct contact and non-contact co-cultures.