Publications

Selected Articles

• Louvi, A., Alexandre, P., Metin, C., Wurst, W., and Wassef, M. (2003). The isthmic neuroepithelium is essential for cerebellar midline fusion. Development 130, 5319-5330.
• Louvi, A.*, Sisodia, S.S., and Grove, E.A. (2004). Presenilin 1 in migration and morphogenesis in the central nervous system. Development 131, 3093- 3105. (*corresponding author)
• Abelson, J. F., Kwan K. Y., O'Roak B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rasin, M.-R., Gunel, M., Davis, N. R., Ercan-Sencicek, A. G., Guez, D. H., Spertus, J. A., Leckman, J. F., Dure, L. S., Kurlan, R., Singer, H. S., Gilbert, D. L., Farhi, A., Louvi, A., Lifton, R.P., Sestan, N., and State, M.W. (2005). Sequence Variants in SLITRK1 Are Associated with Tourette Syndrome. Science 310, 317-320.
• Louvi, A.*, Yoshida, M. and Grove, E.A. (2007). The derivatives of the Wnt3a lineage in the central nervous system. Journal of Comparative Neurology 504, 550-569. (*corresponding author)
• Arboleda-Velasquez, J. F.*, Zhou, Z.*, Shin, H. K., Louvi, A., Kim, H. H., Savitz, S.I., Liao, J. K., Salomone, S., Ayata, C., Moskowitz, M. A., and Artavanis-Tsakonas, S. (2008). Linking Notch signaling to ischemic stroke. Proc. Natl. Acad. Sci. USA. 105, 4856-4861. (*equal contribution)
• Tanriover, G., Boylan, A. J., DiLuna, M. L., Pricola, K. L., Louvi, A., and Gunel, M. (2008). PDCD10, the gene mutated in Cerebral Cavernous Malformation 3 (CCM3) is expressed in the neurovascular unit. Neurosurgery 62, 930-938.
• Stillman, A., Krsnik, Z., Sun, J., Rasin, M.-R., State, M. W., Sestan, N., and Louvi, A. (2009). Developmentally regulated and evolutionarily conserved expression of SLITRK1 in brain circuits implicated in Tourette syndrome. Journal of Comparative Neurology, 513:21-37.
• Chen, L., Tanriover, G., Yano, H., Friedlander, R., Louvi, A. and Gunel, M. (2009) Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3. Stroke 40:1474-1481.
• Bilgüvar, K.*, Oztürk, A. K.*, Louvi, A., Kwan, K. Y., Choi, M., Tatli, B., Yalnizoğlu, D., Tüysüz, B., Cağlayan, A. O., Gökben, S., Kaymakçalan, H., Barak, T., Bakircioğlu, M., Yasuno, K., Ho, W., Sanders, S., Zhu, Y., Yilmaz, S., Dinçer, A., Johnson, M. H., Bronen, R. A., Koçer, N., Per, H., Mane, S., Pamir, M. N., Yalçinkaya, C., Kumandaş, S., Topçu, M., Ozmen, M., Sestan, N., Lifton, R. P., State, M. W., Günel, M. (2010). Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature 467, 207-210. (*equal contribution)
• Louvi, A.*, Chen, L., Two, A. M., Zhang, H., Min, W., and Gunel, M.* (2011). Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology. Proc. Natl. Acad. Sci. USA. 108, 3737-3742. (*corresponding authors)
• Arboleda-Velasquez, J., Manent, J., Lee J. H., Tikka, S., Ospina, C., Vanderburg, C. R., Frosch, M.P., Rodriguez-Falcon, M., Villen, J., Gygi, S., Lopera, F., Kalimo, H., Moskowitz, M. A., Ayata, C., Louvi, A.*, and Artavanis-Tsakonas, S.* (2011). Hypomorphic Notch 3 alleles link Notch signalling to ischemic cerebral small-vessel disease. Proc. Natl. Acad. Sci. USA. 108, E128-135. (*corresponding authors)
• Barak, T.*, Kwan, K. Y.*, Louvi, A., Demirbilek, V., Saygi, S., Tüysüz, B., Choi, M., Boyaci, H., Doerschner, K., Zhu, Y., Kaymakçalan, H., Yilmaz, S., Bakircioğlu, M., Çağlayan, A. O., Öztürk, A. K., Yasuno, K., Brunken, W. J., Atalar, E., Yalçinkaya, C., Dinçer, A., Bronen, R. A., Mane, S., Özçelik, T., Lifton, R. P., Šestan, N., Bilgüvar, K., and Günel, M. (2011). Recessive laminin γ3 mutations cause malformations of occipital cortical development. Nat. Genet. 43, 590-594. (*equal contribution)

Reviews

• Louvi, A. and Artavanis-Tsakonas, S. (2006). Notch signalling in vertebrate neural development. Nature Reviews Neuroscience 7, 93-102.
• Louvi, A., Arboleda-Velasquez, J., and Artavanis-Tsakonas, S. (2006). CADASIL: a critical look at a Notch disease. Developmental Neuroscience 28, 5-12.
• Öztürk, A.K., Louvi, A., Günel, M. (forthcoming, 2011). Genetics of Cerebral Cavernous Malformations. In Youmans Neurological Surgery, 6th edition, ed. H. R. Winn, Elsevier.
• Louvi, A. and Grove, E.A. (2011). Cilia in the CNS: the Quiet Organelle Takes Center Stage. Neuron 69, 1046-1060.