Publications
DeWan A, Liu M, Hartman S, Zhang SS-M, Liu DT, Zhao C, Tam POS, Chan WM, Lam DSC, Snyder M, Barnstable C, Pang CP, Hoh J. HTRA1 Promoter Polymorphism in Wet Age-Related Macular Degeneration. Science. 2006 Nov 10; 314(5801):989-992. AbstractPDF
Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, Pearson E, Li X, Chien J, DeWan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K. A Variant of the HTRA1 Gene Increases Susceptibility to Age-Related Macular Degeneration. Science. 2006 Nov 10; 314(5801): 992-993. AbstractPDF
Zareparsi S, Branham KE, Li M, Shah S, Klein RJ, Ott J, Hoh J, Abecasis GR, Swaroop A. Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet. 2005 Jul;77(1):149-53. Full Text
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J. Complement factor H polymorphism in age-related macular degeneration. Science. 2005 Apr 15;308(5720):385-9. AbstractPDF
Hoh J, Ott J. Genetic dissection of diseases: design and methods. Curr Opin Genet Dev. 2004 Jun;14(3):229-32. Abstract
Hoh J, Ott J. Mathematical multi-locus approaches to localizing complex human trait genes. Nat Rev Genet. 2003 Sep;4(9):701-9. Abstract
Ott J, Hoh J. Set association analysis of SNP case-control and microarray data.
J Comput Biol. 2003;10(3-4):569-74. AbstractPDF
Yang Y, Hoh J, Broger C, Neeb M, Edington J, Lindpaintner K, Ott J. Statistical methods for analyzing microarray feature data with replications.
J Comput Biol. 2003;10(2):157-69. AbstractPDF
Yang Y, Zhang J, Hoh J, Matsuda F, Xu P, Lathrop M, Ott J. Efficiency of single-nucleotide polymorphism haplotype estimation from pooled DNA. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7225-30. AbstractPDF
Hoh J, Matsuda F, Peng X, Markovic D, Lathrop MG, Ott J. SNP haplotype tagging from DNA pools of two individuals. BMC Bioinformatics. 2003 Apr 22;4:14. Epub 2003 Apr 22. AbstractPDF
Acuna G, Foernzler D, Leong D, Rabbia M, Smit R, Dorflinger E, Gasser R, Hoh J, Ott J, Borroni E, To Z, Thompson A, Li J, Hashimoto L, Lindpaintner K. Pharmacogenetic analysis of adverse drug effect reveals genetic variant for susceptibility to liver toxicity. Pharmacogenomics J. 2002;2(5):327-34. AbstractFull Text
Zee RY, Hoh J, Cheng S, Reynolds R, Grow MA, Silbergleit A, Walker K, Steiner L, Zangenberg G, Fernandez-Ortiz A, Macaya C, Pintor E, Fernandez-Cruz A, Ott J, Lindpainter K. Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.
Pharmacogenomics J. 2002;2(3):197-201. AbstractFull Text
Hoh J, Jin S, Parrado T, Edington J, Levine AJ, Ott J. The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8467-72. AbstractPDF
Hoh J, Ott J. A train of thoughts on gene mapping. Theor Popul Biol. 2001 Nov;60(3):149-53. AbstractPDF
Hoh J, Wille A, Ott J. Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res. 2001 Dec;11(12):2115-9. AbstractPDF
Ott J, Hoh J. Statistical multilocus methods for disequilibrium analysis in complex traits. Hum Mutat. 2001 Apr;17(4):285-8. AbstractPDF
Hoh J, Wille A, Zee R, Cheng S, Reynolds R, Lindpaintner K, Ott J. Selecting SNPs in two-stage analysis of disease association data: a model-free approach.
Ann Hum Genet. 2000 Sep;64(Pt 5):413-7. Abstract
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