Selected Publications
Hafler, D.A., Compston, A., Sawcer, S., Lander, S., Daly, M.J., DeJager, P.L., de Bakker, P.I.W., Gabriel, S.B., Mirel, D.B., Ivinson, A.J., Pericak-Vance, M.A., Gregory, S.G., Rioux, J.D., McCauley, J.L., Haines, J.L., Barcellos, L.F., Cree, B., Oksenberg, J.R., Hauser, S.,L. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 30; 357(9):851-62, 2007.
Yang L, Anderson DE, Baecher-Allan C, Bettelli E, Oukka M, Kuchroo VK, Hafler DA, IL-21 and TGF-ß are Required for Differentiation of Human Th17 cells Nature 17;454(7202):350-2, 2008.
Beriou G, Ashley CW, Costantino CM, Yang L, Kuchroo VK, Baecher-Allan C, Hafler DA, IL-17 producing human peripheral regulatory T cells retain suppressive function. Blood, 2009 Apr 30;113(18):4240-9. Epub 2009 Jan 26.
Anderson, AC, Anderson, DE, Bregoli, L, Hastings, WD, Kassam, N, Lei, C, Chandwaskar, R, Karman, J, Su, EW, Hirashima, M, Bruce, JN, Kane, LP, Kuchroo, VK, Hafler, DA. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 318(5853):1141-3 (2007).
Bradshaw EM, Raddassi K, Elyaman W, Orban T, Gottlieb PA, Kent SC, Hafler DA. Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells. J Immunol. 2009 Sep 11. [Epub ahead of print]
Costantino CM, Ploegh HL, Hafler DA, Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells. J Immunol, 2009 Jul 15;183(2):945-52, Epub 2009 Jun 24.
De Jager PL, Baecher-Allan C, Maier LM, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PIW, Tran D, Aubin C, Pobywajlo S, Rossin E, Ashley C, Choy E, Barcellos L, Rioux JD, Pericak-Vance MA, Ivinson A, Palotie A, Peltonen L, Dubois B, Haines JL, Compston A, Hauser SL, Daly MJ, Reich DE, Oksenberg JR, Hafler DA, The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A, 2009 Mar 31;106(13):5264-9. Epub 2009 Feb 23.