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DiMaio Laboratory

Yale University
School of Medicine
Department of Genetics
Department of Therapeutic Radiology
Department of Molecular Biophysics & Biochemistry

Daniel DiMaio
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Lisa Freeman-Cook
ManagerInvitrogen, Carlsbad, CA
B.A. 1994 Carleton College
Ph.D. 1999 University of Colorado, Boulder

Lisa Freeman-Cook


Lockshon, D., Zweifel, S.G., Freeman-Cook, L.L., Lorimer, H.E., Brewer, B.J., and Fangman, W.L. (1995) A role for recombination junctions in the segregation of mitochondrial DNA in yeast. Cell 81:947-955.

Sherman, J.M., Stone, E.M., Freeman-Cook, L.L., Brachmann, C.B., Boeke, J.D., and Pillus, L. (1999) The conserved core of a human SIR2 homologue functions in yeast silencing. Mol. Biol. Cell 10:3045-3059.

Freeman-Cook, L.L., Sherman, J., Brachmann, C., Boeke, J., Nimmo, E., Alshire, R., and Pillus, L. (1999) The S. pombe hst4+ gene is a SIR2 homologue with silencing and centromeric functions. Mol. Biol. Cell 10:3171-3186.

Freeman-Cook, L.L., Dixon, A.M., Frank, J.B., Xia, Y., Ely, L., Gerstein, M., Engelman, D.M., and DiMaio, D. (2004) Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor ß receptor. J. Mol. Biol. 338:907-920.

Freeman-Cook, L.L., Edwards, A.P.B., Dixon, A.M., Yates, K.E., Ely, L., Engelman, D.M., and DiMaio, D. (2005) Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor ß receptor. J. Mol. Biol. 345:907-921.

Freeman-Cook L.L., Gomez EB, Spedale EJ, Marlett J, Forsburg SL, Pillus L, and Laurenson P. (2005) Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+. Genetics 169:1243-1260.

Freeman-Cook, L.L. and DiMaio, D. (2005) Modulation of cell phenotype by small transmembrane proteins modeled on the bovine papillomavirus E5 protein. Oncogene 24: 7756-7762.

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Updated August 15, 2009