Current Lab Members
- Serap Aksoy, Ph.D.
- Geoffrey Attardo, Ph.D.
- Michelle Bailly, M.S.
- Josh Benoit, Ph.D.
- Oleg Kruglov
- Laura Cronin
- Michele Maltz, Ph.D.
- Veronika Michalkova
- Amy Savage, Ph.D.
- Thiago Luiz Alves e Silva
- Erich Telleria, Ph.D.
- Jingwen Wang, Ph.D.
- Brian Weiss, Ph.D.
- Xin Zhao, Ph.D.
- Yineng Wu, M.Sc.
Past Lab Members
- Leyla Akman, Ph.D.
- Uzma Alam, Ph.D.
- Corey Brelsfoard, Ph.D.
- Xiao-ai Chen, Ph.D.
- Quing Cheng, Ph.D.
- Nurper Guz
- Zhengrong Hao, Ph.D.
- Changyun Hu, Ph.D.
- Youjia Hu, Ph.D.
- Song Li, Ph.D.
- Claudia Lohs
- Dana Nayduch, Ph.D.
- Roshan Pais, Ph.D.
- Sarah Perkin, Ph.D.
- Sandesh Regmi, Ph.D.
- Rita Rio, Ph.D.
- Patricia Strickler-Dinglasan Ph.D.
- Guangxiao Yang, Ph.D.
- Jian Yang, Ph.D.
- Suleyman Yildirim, Ph.D.
Brian Weiss
Associate Research Scientist
Lab Phone: (203) 737-4134
Fax: (203) 785-4782
Email: brian.weiss@yale.edu
Education
- Post-doctoral Fellow: Epidemiology and Public Health, Yale University School of Medicine
- Post-doctoral Associate: Epidemiology and Public Health, Yale University School of Medicine
- Ph.D. Physiology and Cell Biology: University of Alberta, 2003
- MSc. Entomology: University of Queensland, 1998
- B.A. Environmental, Population and Organismic Biology: University of Colorado, 1996
Awards, Honors and Grants
- Kirschstein-NRSA training fellowship to Brian Weiss - 2005-2008: 5F32-AI062680 “Gene expression in commensal tsetse symbionts”
- Department of Biological Sciences Excellence in Teaching Award , University of Alberta - 2001+2002
- Graduate Studies and Research Scholarship, University of Alberta - 1998-2003
Curriculum vitae
Publications
Weiss BL, Maltz M, Aksoy S. Obligate symbionts activate immune system development in the tsetse fly. J Immunol. 2012 Apr 1;188(7):3395-403. Epub 2012 Feb 24. PubMed PMID: 22368278; PubMed Central PMCID: PMC3311772.
Weiss BL, Wang J, Aksoy S. Tsetse immune system maturation requires the presence of obligate symbionts in larvae. PLoS Biol. 2011 May;9(5):e1000619. Epub 2011 May 31. PubMed PMID: 21655301; PubMed Central PMCID: PMC3104962.
Weiss, B.L., Attardo, G.M., Aksoy, S. (2009). Insect-protozoa-bacteria associations: a model system for investigating host-parasite interactions. In: Insect Pathogens: Molecular Approaches and Techniques, eds. P. Stock, N. Boemare, I. Glazer, J. Vanderberg, CABI Publishing, Cambridge, MA.
Aksoy S, Weiss B, Attardo G. Paratransgenesis applied for control of tsetse transmitted sleeping sickness. Adv Exp Med Biol. 2008;627:35-48. Review. PubMed PMID: 18510012.
Weiss, B. L., Attardo, G. M., Pais, R., Wang, J. and Aksoy, S. (2007). Novel strategies targeting pathogen transmission reduction in insect vectors: Tsetse-transmitted trypanosomiasis control. Entomological Research, 37: 231–237. doi: 10.1111/j.1748-5967.2007.00119.x
Weiss BL, Wu Y, Schwank JJ, Tolwinski NS, Aksoy S. An insect symbiosis is influenced by bacterium-specific polymorphisms in outer-membrane protein A. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15088-93. Epub 2008 Sep 24. PubMed PMID: 18815366; PubMed Central PMCID: PMC2567497.
Weiss BL, Mouchotte R, Rio RV, Wu YN, Wu Z, Heddi A, Aksoy S. Interspecific transfer of bacterial endosymbionts between tsetse fly species: infection establishment and effect on host fitness. Appl Environ Microbiol. 2006 Nov;72(11):7013-21. Epub 2006 Sep 1. PubMed PMID: 16950907; PubMed Central PMCID: PMC1636136.
Toh H, Weiss BL, Perkin SA, Yamashita A, Oshima K, Hattori M, Aksoy S. Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host. Genome Res. 2006 Feb;16(2):149-56. Epub 2005 Dec 19. PubMed PMID: 16365377; PubMed Central PMCID: PMC1361709.
Weiss BL, Kaufman WR. Two feeding-induced proteins from the male gonad trigger engorgement of the female tick Amblyomma hebraeum. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5874-9. Epub 2004 Apr 6. PubMed PMID: 15069191; PubMed Central PMCID: PMC395891.
Uretsky AD, Weiss BL, Yunker WK, Chang JP. Nitric oxide produced by a novel nitric oxide synthase isoform is necessary for gonadotropin-releasing hormone-induced growth hormone secretion via a cGMP-dependent mechanism. J Neuroendocrinol. 2003 Jul;15(7):667-76. PubMed PMID: 12787051.
Weiss BL, Stepczynski JM, Wong P, Kaufman WR. Identification and characterization of genes differentially expressed in the testis/vas deferens of the fed male tick, Amblyomma hebraeum. Insect Biochem Mol Biol. 2002 Jul;32(7):785-93. PubMed PMID: 12044495.
Weiss BL, Reuben Kaufman W. The relationship between 'critical weight' and 20-hydroxyecdysone in the female ixodid tick, Amblyomma hebraeum. J Insect Physiol. 2001 Nov;47(11):1261-1267. PubMed PMID: 12770177.
Weiss, B.L., Merritt, D.J. (1998). Demonstration of an ecdysis-triggering compound in the epitracheal gland of the cotton bollworm, Helicoverpa armigera (Hubner)(Lepidoptera: Noctuidae). Australian Journal of Entomology 37, 366-368