Stephen C Edberg PhD

Professor Emeritus of Laboratory Medicine

Research Interests

Bacteria; infection; metabolic activity; enzyme production; diarrhea

Research Summary

My research is primarily focused on which characteristics of bacteria make them virulent for human beings. In particular, I am interested in bacteria that are found in the environment that may cause infection in human beings. To determine the virulence characteristics of bacteria, my laboratory has examined a wide variety of bacterial species from the environment and from human clinical infections to determine the most important characteristics associated with invasiveness. The bacteria have been analyzed based on metabolic activity, enzyme production, the ability to attach to and to penetrate into cells and the ability to produce certain DNA sequences that are associated with virulence. My laboratory is now engaged in a major Centers for Disease Control project on the examination of the causes of diarrhea. Patient specimens and age-matched controls are examined for three groups: those which are known; those which are suspected; and those which are speculative. In addition, normal flora bacteria are screened for antibiotic resistance. The Clinical Microbiology laboratory also engages in collegial research with both basic and clinical investigators. Plus, it generates its own projects for the residents and fellows.

Selected Publications

  • Shelley Latte, Emilia Mia Sordillo, Stephen C. Edberg The measurement of antibiotics from human body fluids: techniques and significance. Antibiotics in Laboratory Medicine, 6th edition, Lippincott Williams & Wilkins in press,
  • Stephen C. Edberg Microbial Health Risks of Regulated Drinking Waters in the United States: A Comparative Microbial Safety Assessment of Public Water Supplies and Bottled Water. Advances in Public Health, Intechopen press, in press
  • Stephen C. Edberg Accelerated Detection of Microbes Utilizing an Organic Particle Catalyst in the Total Coliforms and Escherichia coli MM0-MUG (Colilert®) test, Advances in Public Health, Intechopen press, in press.
  • Stephen C. Edberg and J. Michael Miller A New Epidemiological System for the Detection of Antibiotic Resistant Bacteria Advances in Public Health, Intechopen press, in press
  • Stephen Edberg Rapid Detection Tool for Vancomycin-resistant Enterococcus (VRE) Directly from Human Specimens Advances in Microbiology, in press
  • Stephen C. Edberg and J. Michael Miller A New Epidemiological Tool for Staphylococcus aureus Surveillance Advances in Microbiology, in press
  • Allen M.J., Edberg S.C., Clancy J.L., Hrudey S.E. Drinking water microbial myths Crit Rev Microbiol. October: 2013: 1-8

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