Acute Leukemia diagnosis is available with same day turnaround seven days a week (including final diagnostic interpretation by our clinical pathologists). Analysis is carried out in a "reflex marker" approach as appropriate to best subcategorize the disease. Final WHO diagnosis will often include molecular testing as needed. Follow-up minimal residual disease testing can be carried out by flow cytometry criteria as well as by quantitative RT-PCR for common translocations where appropriate (e.g., bcr-abl, 15;17 etc).
The laboratory performs analyses for myelodysplasia as well as MPD and LPD. Detection of small monoclonal populations has been an area of interest – now combined with PCR testing in the molecular laboratory.Immunodeficiencies
The laboratory offers quantitative assessment of critical lymphocytes subsets and works with the Immunology laboratory to establish diagnoses in this area. Transplantation associated immunodeficiency is an area of special interest.
The laboratory has a long-standing interest in evaluating platelet kinetics via reticulated platelet analysis and in use of flow cytometry for functional platelet analysis