Edward L. Snyder, M.D.

Background

B.A., Harpur College State University of New York at Binghamton, 1967
M.A., Harpur College State University of New York at Binghamton, 1969
M.D., New York Medical College, 1973
Fellowship: Hematology/Transfusion Medicine, Montefiore Hospital

Research Interests

Dr. Snyder's research relates to the broad field of Transfusion Medicine and, more specifically, Transfusion Oncology and Transfusion Immunobiology. His current research includes an on-going evaluation of the platelet storage lesion. This includes evaluation of alterations that occur in platelet metabolism during various storage conditions, in the platelet's cystoskeleton and in the mitochondria within platelets. Studies of the in vitro and in vivo aspects of platelet storage are an on-going effort in the laboratory. Dr. Snyder also has a long-term history of investigating the role of leukodepletion in blood components. Most recently, the laboratory has turned to the evaluation of new pathogen reduction technology. This includes the addition of various compounds to blood to remove known and potentially dangerous, as well as unknown, viral, bacterial, and protozoal contaminants in donated blood. The laboratory has a special expertise in radiolabeling human blood cells. The laboratory is currently performing clinical trials related to in vivo recovery and survivals using indium-111 and chromium-51 radiolabeled platelets and red cells, as well as Phase III trials for transfusion of pathogen-reduced blood components into patients. We are also involved in ongoing evaluations of clinical responses of patients to pheresis interventions for a variety of immunologic disorders. This is often done in conjunction with the evaluation of new apheresis machine hardware developed by a variety of corporations.

Clinical and Teaching Activities

Dr. Snyder is Board Certified in Internal Medicine, Hematology, and Transfusion Medicine. His clinical work is aimed at transfusion practice and primarily encompasses classical transfusion medicine, as well as the clinical apheresis service where he is responsible for the oversight of the plasmapheresis, leukapheresis, and plateletpheresis services. We are also involved in the collection and processing of peripheral blood stem cells for the Yale Stem Cell Transplant Program and in the collection of mononuclear cells for donor lymphocyte infusion. Dr. Snyder is the medical director of the Frisbee Laboratory, a Class 10,000 facility for the preparation of cellular therapy products. Dr. Snyder participates in the Department of Laboratory Medicine's T-32 NIH grant for training in immunohematology and transfusion medicine.

Publications

To obtain Dr. Snyder's bibliography on PubMed, please click here:
http://www.ncbi.nlm.nih.gov/pubmed?term=snyder%20el%20and%20yale