10. Coagulation Factor Levels

Coagulation Factor Levels

 
Normal Levels
 Factor II68 %50-150 %
 
 Factor V124 %50-160 %
 
 Factor X4 %50-160 %

Interp: factor X deficiency. No evidence for vitamin K deficiency or rodenticide ingestion

Clinical Course - day 1

  • Received 1U PRBC 1h into admission
  • 4 units FFP given immediately after diagnosis of factor X deficiency
  • Started on Premarin
  • Hct rose to 23.5% within 12 hrs

Clinical Course - days 2-4

  • One additional unit of PRBCs
  • Received 2 units FFP/day
  • Factor X levels rose to >20%
  • Menstrual bleeding stopped
  • Premarin D/C'd, started on Lo/Ovral

Discharge plan

  • Followup in Hematology Clinic
  • Continue Lo/Ovral
  • Resume normal activity but no contact sports
  • Avoid NSAIDs and aspirin
  • The great-aunt with the blood disorder was eventually contacted; she too has factor X deficiency