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- Case Studies
- Case Study 1
- 1. Present Illness
- 2. Break Point
- 3. Social History, Phys. Exam., Lab Eval., Coags, Chest X-Ray
- 4. Break Point
- 5. CAT Scan
- 6. Differential Diagnosis
- 7. Work-up for infection
- 8. Break Point
- 9. Work-up for lymphoma
- 10. Break Point
- 11. Work-up for odynophagia
- 12. Cultures and Stains
- 13. Final Diagnosis
- 14. Mycobacteria and Septic Shock
- 15. Gaucher's Disease
- 16. Identification of Mycobacteria
- 17. Mycobacterial Infections in Renal Transplant Patients
- 18. Tumors After Renal Transplantation
- 19. References
- Case Study 2
- History of Present Illness
- Breakpoint #1
- Past Medical, Social, Family History, Medications, and Allergies
- Admission Physical Examination
- Breakpoint #2
- Summary of Initial Laboratory Values
- Breakpoint #3
- Working Impression
- Findings over the last 72 hours
- Breakpoint #4
- History, Diet, Hyperkeratoic Hair Follicles
- Abscorbic Acid Samples
- Discussion
- Vitamin C Requirements
- Scurvy
- Clinical Assay of Vitamin C Status
- Case Study 3
- 1. History of Present Illness
- 2. Other Past Medical History
- 3. Medications and Allergies
- 4. SH & FH
- 5. PE
- 6. Lab Results
- 7. Dx Imaging
- 8. Assessment
- 9. Breakpoint #1
- 10. A/P
- 11. More Lab Results
- 12. Bone Marrow Aspirate
- 13. Marrow Aspirate Results
- 14. Bone Marrow Biopsy
- 15. BM Aspirate and Biopsy Findings
- 16. BM Flow Cytometry
- 17. Clinical Course
- 18. One Year Later
- 19. Lab Studies
- 20. Clinical Course
- 21. Clinical Course
- 22. One Disease Entity?
- 23. More Lab Results
- 24. Common Variable Immunodeficiency (CVID)
- Case Study 4
- 1. Present Illness
- 2. Breakpoint #1
- 3. Orbital Implants
- 4. Physical Exam
- 5. Initial Plan
- 6. Laboratory Findings: Conjunctival Swab
- 7. Gram Positive Rods
- 8. Laboratory Findings
- 9. Identification of Mycobacteria
- 10. Mycolic Acid Structure
- 11. HPLC
- 12. Final Identification by HPLC
- 13. Drug Susceptibility Testing
- 14. Therapy
- 15. Mycobacterium Chelonae Complex
- 16. Ocular Mycobacterial Infections
- 17. References
- Case Study 5
- 1. Clinical History
- 2. Past Medical History
- 3. Family History
- 4. Work-up of Coagulopathy
- 5. von Willebrand's disease (vWD): historical perspective
- 6. von Willebrand Factor
- 7. Secretion of vWF
- 8. von Willebrand's Disease (vWD)
- 9. Laboratory tests for vWD
- 10. Our Patient's Work-Up
- 11. Summary
- 12. Other Possible Pathophysiology
- 13. Acquired vWD associated with CLL in our patient
- 14. Treatment Plan
- 15. Treatment of vWD
- 16. References
- Case Study 6
- 1. History of Present Illness
- 2. Past Medical History
- 3. Family History
- 4. Physical Exam
- 5. Pelvic Ultrasound
- 6. ER Management
- 7. Special Coag Studies
- 8. Differential Diagnosis
- 9. Chemistry Results
- 10. Coagulation Factor Levels
- 11. Factor X Deficiency
- 12. Activation of Factor X
- 13. Factor X Deficiency
- 14. Molecular Studies
- 15. Acquired FX Deficiency
- 16. Treatment Of Bleeding With FX Deficiency
- Case Study 7
- 1. History of Present Illness
- 2. Early Clinical Course
- 3. Travel and Infectious History
- 4. Diagnostic Imaging
- 5. Further Evaluation on Hospital Day 2
- 6. Brain Biopsy Slides
- 7. Brain Biopsy - Histopathologic Interpretation
- 8. Immunohistochemistry
- 9. Brain Biopsy - Additional Histopathology Results
- 10. HSV-1 Gross Pathology
- 11. HSV-1 Histopathology
- 12. Laboratory Evaluation of Suspected Encephalitis CSF PCR
- 13. Clinical Course in Our Patient
- Case Study 1
- Other Academic Resources
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Education | Online Courses and CME | Case Studies | Case Study 2 | Breakpoint #3
7. Breakpoint #3
Breakpoint #3 - answers on page 8
1) Is the anemia secondary to a primary marrow disorder, red cell destruction, or blood loss?
2) What is the most likely cause of the coagulopathy? What laboratory tests (if any) will establish the diagnosis? Is severe liver disease or DIC likely?
3) How would you image the right leg? What specific entities in the leg must be ruled out?
4) Is this a likely presentation for an occult neoplastic disease? What malignant disorder, if any, is most likely to present in this manner?

