Selected Publications

1. Han L, Kong D, Zheng MQ, Murikinati S, Yuan P, Li L, Tian D, Cai Q, Ye C, Holden D, Park JH, Gao X, Thomas JL, Grutzendler J, Carson RE, Huang Y, Piepmeier JM, Zhou J, Increased nanoparticle delivery to brain tumors by autocatalytic priming for improved treatment and imaging, ACS Nano, 2016 Mar 11. [Epub ahead of print]

2. Han L, Cai Q, Tian D, Kong D, Gou X, Chen Z, Strittmatter SM, Wang Z, Sheth KN, Zhou J, Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, in press


3. Chen Y, Gou X, Kong DK, Wang X, Wang J, Chen Z, Huang C, Zhou J. EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF. Oncotarget. 2015;6(32):32575-85. PubMed PMID: 26416452.


4. Strohbehn G, Coman D, Han L, Ragheb RR, Fahmy TM, Huttner AJ, Hyder F, Piepmeier JM, Saltzman WM, Zhou J. Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. J Neurooncol. 2015;121(3):441-9. PubMed PMID: 25403507; PMCID: 4323763.


5. Cai Q, Chen Z, Kong DK, Wang J, Xu Z, Liu B, Chen Q, Zhou J. Novel microcatheter-based intracarotid delivery approach for MCAO/R mice. Neurosci Lett. 2015;597:127-31. PubMed PMID: 25899778.


6. Ediriwickrema A, Zhou J, Deng Y, Saltzman WM. Multi-layered nanoparticles for combination gene and drug delivery to tumors. Biomaterials. 2014;35(34):9343-54. PubMed PMID: 25112935; PMCID: PMC4155034.


7. Sirianni RW, Zheng MQ, Patel TR, Shafbauer T, Zhou J, Saltzman WM, Carson RE, Huang Y. Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography. Bioconjug Chem. 2014;25(12):2157-65. PubMed PMID: 25322194; PMCID: PMC4275164.


8. Zhou J, Patel TR, Sirianni RW, Strohbehn G, Zheng M-Q, Duong N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ, Jr., Piepmeier JM, Saltzman WM. Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proc Natl Acad Sci U S A. 2013;110(29):11751-6. PubMed PMID: 23818631. (Featured in Nature Reviews Drug Discovery, and Faculty of 1000 Biology).


9. Zhou J, Liu J, Cheng CJ, Patel TR, Weller CE, Piepmeier JM, Jiang Z, Saltzman WM. Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nat Mater. 2012;11(1):82-90. PubMed PMID: 22138789. (Featured in Nature Materials, and Nanomedicine) 


10. Zhou J, Patel TR, Fu M, Bertram JP, Saltzman WM. Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials. 2012;33(2):583-91. PubMed PMID: 22014944.


11. Zhou J, Atsina KB, Himes BT, Strohbehn GW, Saltzman WM. Novel delivery strategies for glioblastoma. Cancer J. 2012;18(1):89-99. PubMed PMID: 22290262; PMCID: 3269656.


12. Patel T, Zhou J, Piepmeier JM, Saltzman WM. Polymeric nanoparticles for drug delivery to the central nervous system. Adv Drug Deliv Rev. 2012;64(7):701-5. PubMed PMID: 22210134; PMCID: PMC3323692.


13. Liu J, Jiang ZZ, Zhou JB, Zhang SM, Saltzman WM. Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery. J Biomed Mater Res A. 2011;96a(2):456-65. PubMed PMID: WOS:000285428700020.


14. Zhou J, Zhang H, Gu P, Margolick JB, Yin D, Zhang Y. Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model. Breast Cancer Res Treat. 2009;115(2):269-77. PubMed PMID: 18506619.


15. Zhou JB, Zhang Y. Preclinical development of cancer stem cell drugs. Expert Opinion on Drug Discovery. 2009;4(7):741-52. PubMed PMID: ISI:000267967500004.


16. Zhou J, Zhang Y. Cancer stem cells: Models, mechanisms and implications for improved treatment. Cell Cycle. 2008;7(10):1360-70. PubMed PMID: 18418062.


17. Tao SC*, Li Y*, Zhou J*, Schnaar RL, Zhang Y, Goldstein IJ, Zhu H, Schneck JP. Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers. Glycobiology. (*equal contribution) 2008;18(10):761-9. PubMed PMID: 18625848; PMCID: PMC2733773.


18. Zhou J, Zhang H, Gu P, Bai J, Margolick JB, Zhang Y. NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res Treat. 2008;111(3):419-27. PubMed PMID: 17965935.


19. Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J, Margolick JB, Liotta LA, Petricoin E, 3rd, Zhang Y. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci U S A. 2007;104(41):16158-63. PubMed PMID: 17911267. (Featured in Faculty of 1000 Biology).


20. Byrne ST, Gu P, Zhou J, Denkin SM, Chong C, Sullivan D, Liu JO, Zhang Y. Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007;51(12):4495-7. PubMed PMID: 17876006; PMCID: PMC2168016.


21. Yin X, Zhou J, Jie C, Xing D, Zhang Y. Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549. Life Sci. 2004;75(18):2233-44. PubMed PMID: 15325848.


22. Zhang H, Wang Z, Zhou J. Cytoplasm prepared from all-trans retinoic acid (ATRA)-treated human hematopoietic progenitor cells induces differentiation of both ATRA sensitive and ATRA resistant leukemia cells. Biol Pharm Bull. 2004;27(4):570-3. PubMed PMID: Medline:15056869.


23. Zhou J, Wang Z, Sun S, Liu M, Zhang H. A rapid method for detecting conformational changes during differentiation and apoptosis of HL60 cells by Fourier-transform infrared spectroscopy. Biotechnol Appl Biochem. 2001;33(Pt 2):127-32. PubMed PMID: 11277866.