Selected Publications

1. Chen Y, Gou X, Kong DK, Wang X, Wang J, Chen Z, Huang C, Zhou J. EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF. Oncotarget. 2015, 6(32):32575-85

2. Strohbehn G, Coman D, Han L, Ragheb RRT, Fahmy TM, Huttner AJ, Hyder F, Piepmeier JM, Saltzman WM, Zhou J. Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. Journal of Neuro-Oncology, 2015, 121(3):441-9.

3. Ediriwickrema A, Zhou J, Deng Y, Saltzman WM. Multi-layered nanoparticles for combination gene and drug delivery to tumors. Biomaterials. 2014, 35(34):9343-54.

4. Zhou J, Patel T, Sirianni R, Strohbehn G, Zheng M, Doung N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ, Piepmeier JM, Saltzman WM. Highly-penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proc Natl Acad Sci U S A, 2013, 110(29): 11751-6. (Featured in Nature Reviews Drug Discovery, and Faculty of 1000 Biology)

5. Zhou J, Patel T, Fu M, Piepmeier JM, Saltzman WM. Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials. 2012, 33(2):583-91. 

6. Patel T, Zhou J, Piepmeier JM, Saltzman WM. Polymeric Nanoparticles for Drug Delivery to the Central Nervous System. Advanced Drug Delivery Reviews. 2012, 64(7):701-5.

7. Zhou J, Garth S, Himes B, Kofi-Buaku A, Saltzman WM. Novel Delivery Strategies for Glioblastoma. Cancer Journal. 2012,18(1):89-99. 

8. Zhou J, Liu J, Jiang Z, Patel T, Weller C, Piepmeier JM, Saltzman WM. Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nature Materials. 2011, 11(1):82-90. (Featured in Nature Materials, Nanomedicine) 

9. Zhou J, Zhang H, Gu P, Bai J, Yin D, and Zhang Y. Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model. Breast Cancer Research Treatment. 2009, 115:269-77. 

10. Zhou J, Zhang Y. Preclinical development and screen of cancer stem cell targeted drugs. Expert Opinion in Drug Discovery. 2009, 4(7):741-52. 

11. Zhou J, Zhang H, Gu P, Margolick JB, Zhang Y. Identification of NF- B pathway inhibitors preferentially inhibit breast cancer stem cells. Breast Cancer Research Treatment. 2008, 111(3):419-27. 

12. Tao SC*, Li Y*, Zhou J*, Qian J, Schnaar RL, Goldstein IJ, Zhang Y, Zhu H, Schneck JP. Use of mammalian cell surface glycan signatures in pathogen tropism, cell differentiation, and biomarker identification. (*equal contribution) Glycobiology, 2008, 18(10):761-69. 

13. Zhou J, Zhang Y. Cancer stem cells: models, mechanisms and implications for improved treatment. Cell Cycle. 2008, 7(10):1360-70.

14. Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Margolick JB, Liotta LA, Petricoin III E, and ZhangY. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci U S A. 2007, 41(104):16158-63. (Featured in Faculty of 1000 Biology)

15. Zhou J, Wang Z, Sun SQ, Zhang HJ. A rapid method for detecting conformational changes of differentiation and apoptosis HL60 cells by Fourier Transform Infrared Spectroscopy. Biotechnology and Applied Biochemistry. 2001, 33:127-32.