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Welcome to Yun Lab!

Research

My lab focuses on two main areas of research with a goal to provide pertinent insights for the mechanistic understanding of human diseases.

First, we are interested in understanding the mechanisms by which the tissue or niche microenvironment regulates stem cell maintenance as well as their cell fate. We are particularly interested in regulation of cancer stem cell functions by hypoxia or oxygen deficiency.

The second area of our research concerns the role of oxygen-sensing pathway in the regulation of energy homeostasis, in the pathological progression of obesity, and in obesity-associated metabolic syndromes including type 2 diabetes and cardiovascular diseases.

Research Interests

Cancer Stem Cells, Tumor Hypoxia, Tumor Microenvironment, Obesity, Metabolic Diseases

Yun Lab

Zhong Yun, PhD

Associate Professor of Therapeutic Radiology

Contact Info
Lab
Hunter Building
15 York Street
New Haven, CT 06510

zhong.yun@yale.edu