Welcome to the Yarbrough Laboratory for Head and Neck Oncology at Yale!
Our lab is on the cutting edge of determining molecular defects in tumors that arise in the salivary glands and upper aerodigestive tract (mouth, nose/sinus, throat, voicebox, skin).
Our overall goal is to use molecular characteristics of tumors to develop more effective therapy. New therapies are tested in cell lines, primary tumors grown in culture and patient-derived tumor xenografts that we have developed.
We also examine basic mechanisms of tumor suppression and have developed genetically engineered mouse models that assist with these studies.