Gale M and Yan Q: High-throughput screening to identify inhibitors of lysine demethylases. Epigenomics. 2015 Feb;7 (1) :57-65. PMID: 25687466

Colavito SA, Zou MR, Yan Q, Nguyen DX and Stern DF: Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway. Breast Cancer Res. 2014 Sep 25;16 (5) :444. Epub 2014 Sep 25. PMID: 25252859

Zou MR, Cao J, Liu Z, Huh SJ, Polyak K and Yan Q: Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem. 2014 Jun 20;289 (25) :17620-33. Epub 2014 May 6. PMID: 24802759

Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX and Yan Q: Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep. 2014 Mar 13;6 (5) :868-77. Epub 2014 Feb 27. PMID: 24582965

Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD and Juan LJ: Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis. Cancer Res. 2013 Aug 1;73 (15) :4711-21. Epub 2013 May 30. PMID: 23722541

Cao J and Yan Q: Histone demethylases set the stage for cancer metastasis. Sci Signal. 2013 Apr 30;6 (273) :pe15, 1-2. Epub 2013 Apr 30. PMID: 23633674

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS and Yan Q: Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem. 2013 Mar 29;288 (13) :9408-17. Epub 2013 Feb 13. PMID: 23408432

Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG Jr and Benevolenskaya EV: Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. Proc Natl Acad Sci U S A. 2012 Nov 6;109 (45) :18499-504. Epub 2012 Oct 23. PMID: 23093672

Blair LP and Yan Q: Epigenetic mechanisms in commonly occurring cancers. DNA Cell Biol. 2012 Oct;31 Suppl 1 :S49-61. Epub 2012 Apr 20. PMID: 22519822

Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q and Yang H: The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene. 2012 Feb 9;31 (6) :776-86. Epub 2011 Jul 4. PMID: 21725364

Cao J and Yan Q: Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer. Front Oncol. 2012;2 :26. Epub 2012 Mar 12. PMID: 22649782

Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson RT, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG Jr and Yan Q: Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc Natl Acad Sci U S A. 2011 Aug 16;108 (33) :13379-86. Epub 2011 Jul 25. PMID: 21788502

Blair LP, Cao J, Zou MR, Sayegh J and Yan Q: Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer. Cancers (Basel). 2011 Mar 1;3 (1) :1383-404. PMID: 21544224

Yan Q and Wajapeyee N: Exploiting cellular senescence to treat cancer and circumvent drug resistance. Cancer Biol Ther. 2010 Feb;9 (3) :166-75. Epub 2010 Feb 11. PMID: 20118655

van Oevelen C, Wang J, Asp P, Yan Q, Kaelin WG Jr, Kluger Y and Dynlacht BD: A role for mammalian Sin3 in permanent gene silencing. Mol Cell. 2008 Nov 7;32 (3) :359-70. PMID: 18995834

Yang H, Minamishima YA, Yan Q, Schlisio S, Ebert BL, Zhang X, Zhang L, Kim WY, Olumi AF and Kaelin WG Jr: pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2. Mol Cell. 2007 Oct 12;28 (1) :15-27. PMID: 17936701

Li L, Zhang L, Zhang X, Yan Q, Minamishima YA, Olumi AF, Mao M, Bartz S and Kaelin WG Jr: Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. Mol Cell Biol. 2007 Aug;27 (15) :5381-92. Epub 2007 May 25. PMID: 17526729

Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y and Kaelin WG Jr: The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell. 2007 Mar 9;128 (5) :889-900. Epub 2007 Feb 22. PMID: 17320163

Yan Q, Bartz S, Mao M, Li L and Kaelin WG Jr: The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol Cell Biol. 2007 Mar;27 (6) :2092-102. Epub 2007 Jan 12. PMID: 17220275

Blanchette P, Cheng CY, Yan Q, Ketner G, Ornelles DA, Dobner T, Conaway RC, Conaway JW and Branton PE: Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Mol Cell Biol. 2004 Nov;24 (21) :9619-29. PMID: 15485928

Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC and Conaway JW: Identification of Elongin C and Skp1 sequences that determine Cullin selection. J Biol Chem. 2004 Oct 8;279 (41) :43019-26. Epub 2004 Jul 27. PMID: 15280393

Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D, Kaelin WG, Conaway RC, Conaway JW and Branton PE: Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev. 2001 Dec 1;15 (23) :3104-17. PMID: 11731475

Kamura T, Burian D, Yan Q, Schmidt SL, Lane WS, Querido E, Branton PE, Shilatifard A, Conaway RC and Conaway JW: Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. J Biol Chem. 2001 Aug 10;276 (32) :29748-53. Epub 2001 May 30. PMID: 11384984

Elmendorf BJ, Shilatifard A, Yan Q, Conaway JW and Conaway RC: Transcription factors TFIIF, ELL, and Elongin negatively regulate SII-induced nascent transcript cleavage by non-arrested RNA polymerase II elongation intermediates. J Biol Chem. 2001 Jun 22;276 (25) :23109-14. Epub 2001 Mar 19. PMID: 11259417

Yan Q, Moreland RJ, Conaway JW and Conaway RC: Dual roles for transcription factor IIF in promoter escape by RNA polymerase II. J Biol Chem. 1999 Dec 10;274 (50) :35668-75. PMID: 10585446

Kamura T, Conrad MN, Yan Q, Conaway RC and Conaway JW: The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev. 1999 Nov 15;13 (22) :2928-33. PMID: 10579999

Moreland RJ, Tirode F, Yan Q, Conaway JW, Egly JM and Conaway RC: A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II. J Biol Chem. 1999 Aug 6;274 (32) :22127-30. PMID: 10428772

Conaway JW, Dvir A, Moreland RJ, Yan Q, Elmendorf BJ, Tan S and Conaway RC: Mechanism of promoter escape by RNA polymerase II. Cold Spring Harb Symp Quant Biol. 1998;63 :357-64. PMID: 10384300