Publications

1.

The RtcB RNA ligase is an essential component of the metazoan unfolded protein response.

Kosmaczewski SG, Edwards TJ, Han SM, Eckwahl MJ, Meyer BI, Peach S, Hesselberth JR, Wolin SL, Hammarlund M.

EMBO Rep. 2014 Nov 3; Epub 2014 Nov 3. PMID: 25366321

2.

Bacterial noncoding Y RNAs are widespread and mimic tRNAs.

Chen X, Sim S, Wurtmann EJ, Feke A, Wolin SL.

RNA. 2014 Nov;20 (11) :1715-24. Epub 2014 Sep 17. PMID: 25232022

3.

Non-coding Y RNAs as tethers and gates: Insights from bacteria.

Wolin SL, Belair C, Boccitto M, Chen X, Sim S, Taylor DW, Wang HW.

RNA Biol. 2013 Oct;10 (10) :1602-8. Epub 2013 Aug 22. PMID: 24036917

4.

Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus.

Reed JH, Sim S, Wolin SL, Clancy RM, Buyon JP.

J Immunol. 2013 Jul 1;191 (1) :110-6. Epub 2013 May 22. PMID: 23698747

5.

An RNA degradation machine sculpted by Ro autoantigen and noncoding RNA.

Chen X, Taylor DW, Fowler CC, Galan JE, Wang HW, Wolin SL.

Cell. 2013 Mar 28;153 (1) :166-77. PMID: 23540697

6.

Nuclear noncoding RNA surveillance: is the end in sight?

Wolin SL, Sim S, Chen X.

Trends Genet. 2012 Jul;28 (7) :306-13. Epub 2012 Apr 2. PMID: 22475369

7.

Yeast Gis2 and its human ortholog CNBP are novel components of stress-induced RNP granules.

Rojas M, Farr GW, Fernandez CF, Lauden L, McCormack JC, Wolin SL.

PLoS One. 2012;7 (12) :e52824. Epub 2012 Dec 21. PMID: 23285195

8.

The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA.

Sim S, Yao J, Weinberg DE, Niessen S, Yates JR 3rd, Wolin SL.

RNA. 2012 Jan;18 (1) :100-10. Epub 2011 Nov 23. PMID: 22114317

9.

Emerging roles for the Ro 60-kDa autoantigen in noncoding RNA metabolism.

Sim S, Wolin SL.

Wiley Interdiscip Rev RNA. 2011 Sep-Oct;2 (5) :686-99. Epub 2011 Apr 21. PMID: 21823229

10.

An intrinsically disordered C terminus allows the La protein to assist the biogenesis of diverse noncoding RNA precursors.

Kucera NJ, Hodsdon ME, Wolin SL.

Proc Natl Acad Sci U S A. 2011 Jan 25;108 (4) :1308-13. Epub 2011 Jan 6. PMID: 21212361

11.

Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.

Hamill S, Wolin SL, Reinisch KM.

Proc Natl Acad Sci U S A. 2010 Aug 24;107 (34) :15045-50. Epub 2010 Aug 9. PMID: 20696927

12.

A role for a bacterial ortholog of the Ro autoantigen in starvation-induced rRNA degradation.

Wurtmann EJ, Wolin SL.

Proc Natl Acad Sci U S A. 2010 Mar 2;107 (9) :4022-7. Epub 2010 Feb 16. PMID: 20160119

13.

Packaging of host mY RNAs by murine leukemia virus may occur early in Y RNA biogenesis.

Garcia EL, Onafuwa-Nuga A, Sim S, King SR, Wolin SL, Telesnitsky A.

J Virol. 2009 Dec;83 (23) :12526-34. Epub 2009 Sep 23. PMID: 19776129

14.

The subcellular distribution of an RNA quality control protein, the Ro autoantigen, is regulated by noncoding Y RNA binding.

Sim S, Weinberg DE, Fuchs G, Choi K, Chung J, Wolin SL.

Mol Biol Cell. 2009 Mar;20 (5) :1555-64. Epub 2008 Dec 30. PMID: 19116308

15.

RNA under attack: cellular handling of RNA damage.

Wurtmann EJ, Wolin SL.

Crit Rev Biochem Mol Biol. 2009 Jan-Feb;44 (1) :34-49. PMID: 19089684

16.

Visual analysis of the yeast 5S rRNA gene transcriptome: regulation and role of La protein.

French SL, Osheim YN, Schneider DA, Sikes ML, Fernandez CF, Copela LA, Misra VA, Nomura M, Wolin SL, Beyer AL.

Mol Cell Biol. 2008 Jul;28 (14) :4576-87. Epub 2008 May 12. PMID: 18474615

17.

Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation.

Copela LA, Fernandez CF, Sherrer RL, Wolin SL.

RNA. 2008 Jun;14 (6) :1214-27. Epub 2008 May 2. PMID: 18456844

18.

An ortholog of the Ro autoantigen functions in 23S rRNA maturation in D. radiodurans.

Chen X, Wurtmann EJ, Van Batavia J, Zybailov B, Washburn MP, Wolin SL.

Genes Dev. 2007 Jun 1;21 (11) :1328-39. Epub 2007 May 17. PMID: 17510283

19.

Emerging themes in non-coding RNA quality control.

Reinisch KM, Wolin SL.

Curr Opin Struct Biol. 2007 Apr;17 (2) :209-14. Epub 2007 Mar 28. PMID: 17395456

20.

Structural and biochemical basis for misfolded RNA recognition by the Ro autoantigen.

Fuchs G, Stein AJ, Fu C, Reinisch KM, Wolin SL.

Nat Struct Mol Biol. 2006 Nov;13 (11) :1002-9. Epub 2006 Oct 15. PMID: 17041599

21.

The Ro 60 kDa autoantigen comes into focus: interpreting epitope mapping experiments on the basis of structure.

Wolin SL, Reinisch KM.

Autoimmun Rev. 2006 Jul;5 (6) :367-72. Epub 2005 Nov 15. PMID: 16890888

22.

The La protein functions redundantly with tRNA modification enzymes to ensure tRNA structural stability.

Copela LA, Chakshusmathi G, Sherrer RL, Wolin SL.

RNA. 2006 Apr;12 (4) :644-54. PMID: 16581807

23.

Structural insights into RNA quality control: the Ro autoantigen binds misfolded RNAs via its central cavity.

Stein AJ, Fuchs G, Fu C, Wolin SL, Reinisch KM.

Cell. 2005 May 20;121 (4) :529-39. PMID: 15907467

24.

An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5.

Fernandez CF, Pannone BK, Chen X, Fuchs G, Wolin SL.

Mol Biol Cell. 2004 Jun;15 (6) :2842-52. Epub 2004 Apr 9. PMID: 15075370

25.

The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity.

Chen X, Wolin SL.

J Mol Med (Berl). 2004 Apr;82 (4) :232-9. PMID: 15168680

26.

Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch.

Dong G, Chakshusmathi G, Wolin SL, Reinisch KM.

EMBO J. 2004 Mar 10;23 (5) :1000-7. Epub 2004 Feb 19. PMID: 14976553

27.

The Ro autoantigen binds misfolded U2 small nuclear RNAs and assists mammalian cell survival after UV irradiation.

Chen X, Smith JD, Shi H, Yang DD, Flavell RA, Wolin SL.

Curr Biol. 2003 Dec 16;13 (24) :2206-11. PMID: 14680639

28.

A La protein requirement for efficient pre-tRNA folding.

Chakshusmathi G, Kim SD, Rubinson DA, Wolin SL.

EMBO J. 2003 Dec 15;22 (24) :6562-72. PMID: 14657028

29.

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.

Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T, Yang DD, Eynon E, Brash DE, Kashgarian M, Flavell RA, Wolin SL.

Proc Natl Acad Sci U S A. 2003 Jun 24;100 (13) :7503-8. Epub 2003 Jun 3. PMID: 12788971

30.

The La protein.

Wolin SL, Cedervall T.

Annu Rev Biochem. 2002;71 :375-403. Epub 2001 Nov 9. PMID: 12045101