Sandra L Wolin MD, PhD

Professor of Cell Biology and of Molecular Biophysics and Biochemistry; Director, Yale Center for RNA Science and Medicine

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Microbiology | Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Stem Cell Center, Yale: Transcriptional Regulation of Stem and Progenitor Cells

Radiobiology & Radiotherapy

Center for RNA Science and Medicine, Yale

Cell Biology: Cell Biology of RNA | Developmental Cell Biology and Genetics


Molecular Biophysics and Biochemistry

Research Interests

Noncoding RNAs; RNA surveillance; RNA damage; Autoimmune disease; Environmental stress more...


  • M.D., Yale University, 1985
  • Ph.D., Yale University, 1985

Selected Publications

  • Chen, X., Sim, S., Wurtmann, E.J., Feke, A. and Wolin, S.L. (2014). Bacterial noncoding Y RNAs are widespread and mimic tRNAs. RNA 20, 1715-24.
  • Chen, X., Taylor, D.W., Fowler, C.C., Galan, J.E., Wang, H.-W., Wolin, S.L. (2013). An RNA degradation machine sculpted by Ro autoantigen and noncoding RNA. Cell 153, 166-177.
  • Wolin, S.L., Sim, S. and Chen, X. (2012). Nuclear noncoding RNA surveillance: is the end in sight? Trends Genet. 28, 306-313.



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