Publications

Zhang Q, Miller C, Bible J, Li J, Xu X, Mehta N, Gilligan J, Vignery A and Scholz JA: Additive Effects of Mechanical Marrow Ablation and PTH Treatment on de Novo Bone Formation in Mature Adult Rats. Cells. 2012 Dec 5;1 (4) :1168-81. Epub 2012 Dec 5. PMID: 24710549

Jin C, Frayssinet P, Pelker R, Cwirka D, Hu B, Vignery A, Eisenbarth SC and Flavell RA: NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy. Proc Natl Acad Sci U S A. 2011 Sep 6;108 (36) :14867-72. Epub 2011 Aug 19. PMID: 21856950

Kang H, Chang W, Hurley M, Vignery A and Wu D: Important roles of PI3Kgamma in osteoclastogenesis and bone homeostasis. Proc Natl Acad Sci U S A. 2010 Jul 20;107 (29) :12901-6. Epub 2010 Jul 2. PMID: 20616072


Zhang Q, Carlson J, Ke HZ, Li J, Kim M, Murphy K, Mehta N, Gilligan J and Vignery A: Dramatic increase in cortical thickness induced by femoral marrow ablation followed by a 3-month treatment with PTH in rats. J Bone Miner Res. 2010 Jun;25 (6) :1350-9. PMID: 20200940

Carlson J, Cui W, Zhang Q, Xu X, Mercan F, Bennett AM and Vignery A: Role of MKP-1 in osteoclasts and bone homeostasis. Am J Pathol. 2009 Oct;175 (4) :1564-73. Epub 2009 Sep 17. PMID: 19762714


Carlson J, Zhang Q, Bennett A and Vignery A: Deletion of mitogen-activated protein kinase phosphatase 1 modifies the response to mechanical bone marrow ablation in a mouse model. Comp Med. 2009 Jun;59 (3) :221-6. PMID: 19619411

Zhang Q, Cuartas E, Mehta N, Gilligan J, Ke HZ, Saltzman WM, Kotas M, Ma M, Rajan S, Chalouni C, Carlson J and Vignery A: Replacement of bone marrow by bone in rat femurs: the bone bioreactor. Tissue Eng Part A. 2008 Feb;14 (2) :237-46. PMID: 18333776


Vignery A: Methods to fuse macrophages in vitro. Methods Mol Biol. 2008;475 :383-95. PMID: 18979256


Vignery A: Macrophage fusion: molecular mechanisms. Methods Mol Biol. 2008;475 :149-61. PMID: 18979243

Cui W, Cuartas E, Ke J, Zhang Q, Einarsson HB, Sedgwick JD, Li J and Vignery A: CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts. Proc Natl Acad Sci U S A. 2007 Sep 4;104 (36) :14436-41. Epub 2007 Aug 28. PMID: 17726108


Chen EH, Grote E, Mohler W and Vignery A: Cell-cell fusion. FEBS Lett. 2007 May 22;581 (11) :2181-93. Epub 2007 Mar 21. PMID: 17395182

Cui W, Ke JZ, Zhang Q, Ke HZ, Chalouni C and Vignery A: The intracellular domain of CD44 promotes the fusion of macrophages. Blood. 2006 Jan 15;107 (2) :796-805. Epub 2005 Sep 29. PMID: 16195325

van den Berg TK, van Beek EM, Bühring HJ, Colonna M, Hamaguchi M, Howard CJ, Kasuga M, Liu Y, Matozaki T, Neel BG, Parkos CA, Sano S, Vignery A, Vivier E, Wright M, Zawatzky R and Barclay AN: A nomenclature for signal regulatory protein family members. J Immunol. 2005 Dec 15;175 (12) :7788-9. PMID: 16339511


Vignery A: [Macrophage fusion: are somatic and cancer cells possible partners?]. Med Sci (Paris). 2005 Dec;21 (12) :1070-5. PMID: 16324648


Vignery A: Macrophage fusion: the making of osteoclasts and giant cells. J Exp Med. 2005 Aug 1;202 (3) :337-40. PMID: 16061722


Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Ke HZ, Kobayashi KS, Flavell RA and Vignery A: IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. J Exp Med. 2005 Apr 4;201 (7) :1169-77. PMID: 15809356


Vignery A: Macrophage fusion: are somatic and cancer cells possible partners? Trends Cell Biol. 2005 Apr;15 (4) :188-93. PMID: 15817374

Lesclous P, Guez D, Baroukh B, Vignery A and Saffar JL: Histamine participates in the early phase of trabecular bone loss in ovariectomized rats. Bone. 2004 Jan;34 (1) :91-9. PMID: 14751566

Buehler J, Chappuis P, Saffar JL, Tsouderos Y and Vignery A: Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis). Bone. 2001 Aug;29 (2) :176-9. PMID: 11502480

Han X, Sterling H, Chen Y, Saginario C, Brown EJ, Frazier WA, Lindberg FP and Vignery A: CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation. J Biol Chem. 2000 Dec 1;275 (48) :37984-92. PMID: 10964914


Vignery A: Osteoclasts and giant cells: macrophage-macrophage fusion mechanism. Int J Exp Pathol. 2000 Oct;81 (5) :291-304. PMID: 11168677


Millet I, Phillips RJ, Sherwin RS, Ghosh S, Voll RE, Flavell RA, Vignery A and Rincón M: Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide. J Biol Chem. 2000 May 19;275 (20) :15114-21. PMID: 10809748

Ballica R, Valentijn K, Khachatryan A, Guerder S, Kapadia S, Gundberg C, Gilligan J, Flavell RA and Vignery A: Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice. J Bone Miner Res. 1999 Jul;14 (7) :1067-74. PMID: 10404006

Sterling H, Saginario C and Vignery A: CD44 occupancy prevents macrophage multinucleation. J Cell Biol. 1998 Nov 2;143 (3) :837-47. PMID: 9813101


Saginario C, Sterling H, Beckers C, Kobayashi R, Solimena M, Ullu E and Vignery A: MFR, a putative receptor mediating the fusion of macrophages. Mol Cell Biol. 1998 Nov;18 (11) :6213-23. PMID: 9774638


Millet I, McCarthy TL and Vignery A: Regulation of interleukin-6 production by prostaglandin E2 in fetal rat osteoblasts: role of protein kinase A signaling pathway. J Bone Miner Res. 1998 Jul;13 (7) :1092-100. PMID: 9661073

Millet I and Vignery A: The neuropeptide calcitonin gene-related peptide inhibits TNF-alpha but poorly induces IL-6 production by fetal rat osteoblasts. Cytokine. 1997 Dec;9 (12) :999-1007. PMID: 9417811


Valentijn K, Gutow AP, Troiano N, Gundberg C, Gilligan JP and Vignery A: Effects of calcitonin gene-related peptide on bone turnover in ovariectomized rats. Bone. 1997 Sep;21 (3) :269-74. PMID: 9276092


Khachatryan A, Guerder S, Palluault F, Cote G, Solimena M, Valentijn K, Millet I, Flavell RA and Vignery A: Targeted expression of the neuropeptide calcitonin gene-related peptide to beta cells prevents diabetes in NOD mice. J Immunol. 1997 Feb 1;158 (3) :1409-16. PMID: 9013986

Saginario C, Qian HY and Vignery A: Identification of an inducible surface molecule specific to fusing macrophages. Proc Natl Acad Sci U S A. 1995 Dec 19;92 (26) :12210-4. PMID: 8618871


Vignery A: Bone cell defects in osteogenesis imperfecta. Connect Tissue Res. 1995;31 (4) :275-8. PMID: 15612367

Wang F, Millet I, Bottomly K and Vignery A: Calcitonin gene-related peptide inhibits interleukin 2 production by murine T lymphocytes. J Biol Chem. 1992 Oct 15;267 (29) :21052-7. PMID: 1383217

Vignery A, Raymond MJ, Qian HY, Wang F and Rosenzweig SA: Multinucleated rat alveolar macrophages express functional receptors for calcitonin. Am J Physiol. 1991 Dec;261 (6 Pt 2) :F1026-32. PMID: 1721493


Vignery A, Wang F and Ganz MB: Macrophages express functional receptors for calcitonin-gene-related peptide. J Cell Physiol. 1991 Nov;149 (2) :301-6. PMID: 1721072


Vignery A, Wang F, Qian HY, Benz EJ Jr and Gilmore-Hebert M: Detection of the Na(+)-K(+)-ATPase alpha 3-isoform in multinucleated macrophages. Am J Physiol. 1991 May;260 (5 Pt 2) :F704-9. PMID: 1852120

Vignery A: Macrophage multinucleation is accompanied by the expression of new soluble and membrane antigens in mice. Am J Pathol. 1989 Sep;135 (3) :565-70. PMID: 2675626


Vignery A, Niven-Fairchild T, Ingbar DH and Caplan M: Polarized distribution of Na+,K+-ATPase in giant cells elicited in vivo and in vitro. J Histochem Cytochem. 1989 Aug;37 (8) :1265-71. PMID: 2546991

Baron R, Neff L, Tran Van P, Nefussi JR and Vignery A: Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multinucleated osteoclasts. Am J Pathol. 1986 Feb;122 (2) :363-78. PMID: 3946557


Lang R, Vignery AM and Jensen PS: Fibrogenesis imperfecta ossium with early onset: observations after 20 years of illness. Bone. 1986;7 (4) :237-46. PMID: 3490268

Stewart AF, Hoecker JL, Mallette LE, Segre GV, Amatruda TT Jr and Vignery A: Hypercalcemia in pheochromocytoma. Evidence for a novel mechanism. Ann Intern Med. 1985 Jun;102 (6) :776-9. PMID: 3994189

Horowitz M, Vignery A, Gershon RK and Baron R: Thymus-derived lymphocytes and their interactions with macrophages are required for the production of osteoclast-activating factor in the mouse. Proc Natl Acad Sci U S A. 1984 Apr;81 (7) :2181-5. PMID: 6609360


Insogna KL, Stewart AF, Vignery AM, Weir EC, Namnum PA, Baron RE, Kirkwood JM, Deftos LM and Broadus AE: Biochemical and histomorphometric characterization of a rat model for humoral hypercalcemia of malignancy. Endocrinology. 1984 Mar;114 (3) :888-96. PMID: 6546543


Baron R, Tross R and Vignery A: Evidence of sequential remodeling in rat trabecular bone: morphology, dynamic histomorphometry, and changes during skeletal maturation. Anat Rec. 1984 Jan;208 (1) :137-45. PMID: 6711834

Rodan SB, Insogna KL, Vignery AM, Stewart AF, Broadus AE, D'Souza SM, Bertolini DR, Mundy GR and Rodan GA: Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells. J Clin Invest. 1983 Oct;72 (4) :1511-5. PMID: 6685137


Gewirtz AM, Stewart AF, Vignery A and Hoffman R: Hypercalcaemia complicating acute myelogenous leukaemia: a syndrome of multiple aetiologies. Br J Haematol. 1983 May;54 (1) :133-41. PMID: 6573910


Simmons DJ, Russell JE, Winter F, Tran Van P, Vignery A, Baron R, Rosenberg GD and Walker WV: Effect of spaceflight on the non-weight-bearing bones of rat skeleton. Am J Physiol. 1983 Mar;244 (3) :R319-26. PMID: 6829791


Baron R, Gertner JM, Lang R and Vignery A: Increased bone turnover with decreased bone formation by osteoblasts in children with osteogenesis imperfecta tarda. Pediatr Res. 1983 Mar;17 (3) :204-7. PMID: 6835724

Nefussi JR, Vignery A, Puzas JE and Baron R: Histomorphometry and autoradiography of cultured fetal rat long bones. Anat Rec. 1982 Oct;204 (2) :105-12. PMID: 7181126


Stewart AF, Vignery A, Silverglate A, Ravin ND, LiVolsi V, Broadus AE and Baron R: Quantitative bone histomorphometry in humoral hypercalcemia of malignancy: uncoupling of bone cell activity. J Clin Endocrinol Metab. 1982 Aug;55 (2) :219-27. PMID: 7085851


Tran Van PT, Vignery A and Baron R: Cellular kinetics of the bone remodeling sequence in the rat. Anat Rec. 1982 Apr;202 (4) :445-51. PMID: 7072987


Tran Van P, Vignery A and Baron R: An electron-microscopic study of the bone-remodeling sequence in the rat. Cell Tissue Res. 1982;225 (2) :283-92. PMID: 7105150

Lang R, Milkman M, Jensen PS and Vignery AM: Chronic treatment of Paget's disease of bone with synthetic human calcitonin. Yale J Biol Med. 1981 Sep-Oct;54 (5) :355-65. PMID: 7336766

Simmons DJ, Russell JE, Winter F, Baron R, Vignery A, Tran VT, Rosenberg GD and Walker W: Bone growth in the rat mandible during space flight. Physiologist. 1980 Dec;23 (Suppl 6) :S87-90. PMID: 7243947


Vignery A and Baron R: Dynamic histomorphometry of alveolar bone remodeling in the adult rat. Anat Rec. 1980 Feb;196 (2) :191-200. PMID: 7416512

Puzas JE, Vignery A and Rasmussen H: Isolation of specific bone cell types by free-flow electrophoresis. Calcif Tissue Int. 1979 Jul 3;27 (3) :263-8. PMID: 114288


Vignery A: [Structure, origin and role of the matrix vesicles in bone and cartilage]. Inf Dent. 1979 Jun 7;61 (23) :2041-50. PMID: 393621

Vignery A and Baron R: Effects of parathyroid hormone on the osteoclastic pool, bone resorption and formation in rat alveolar bone. Calcif Tissue Res. 1978 Nov 10;26 (1) :23-8. PMID: 737549