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Summary
The ability to develop immunological memory to infectious diseases is critical for health and survival. Our laboratory studies how this long-term immunity is established and maintained in order to better understand natural immunity, improve vaccine design and develop more effective therapies for autoimmune disease.
Memory B cells that differentiate into antigen presenting and antibody-producing cells are important in natural and vaccine-mediated protection and are targets of B cell-directed therapies for malignancy and autoimmune disease.