Ensign Professor of Therapeutic Radiology and Professor of Genetics
Vice-Chair for Basic Research
Associate Director, Basic Science, Yale Cancer Center
DNA Repair; DNA Replication; Genetics; Mutagenesis; Radiation Oncology; Carcinogenesis
I am an expert in the genetics, cell biology, mutagenesis and biochemistry of DNA repair and cancer and have been funded continuously by the NIH since 1994. A major focus of my laboratory is to understand how single nucleotide polymorphisms in DNA repair genes, including genes that function in homology directed repair (HDR), nonhomologous end-joining (NHEJ) and base excision repair (BER) in the germline and somatic tissues impact cancer risk and treatment. We have recently found that RAD51,...