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Cardiovascular Molecular Imaging Laboratory

The ultimate goal of research in our laboratory is to develop novel in vivo imaging approaches to visualize, characterize and quantify molecular and cellular processes involved in the development of cardiovascular diseases. This is a comprehensive, multi-disciplinary effort, involving the researchers with expertise in vascular and molecular biology, molecular imaging, medical physics and chemistry. Our primary focus is on vascular remodeling and inflammation; key features of atherosclerosis, graft arteriosclerosis, post-angioplasty restenosis, aneurysm and calcific aortic valve disease.

Sadeghi Lab team members in the lab

Research

Despite remarkable recent progress in molecular and vascular biology research, little has been achieved in adapting traditional imaging modalities to detect molecular pathobiology in vivo.